RecruitingPhase 1NCT05003388
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for MS
Sponsor: The Foundation for Orthopaedics and Regenerative Medicine
Naples, FL
Phase 1 Multiple Sclerosis clinical trials
19 recruiting Phase 1 multiple sclerosis studies in the US. What trial phases mean
Other phases
RecruitingPhase 1NCT07304154
Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment
Sponsor: Kite, A Gilead Company
Newport Beach, CA · Palo Alto, CA · New York, NY · +2 more sites
RecruitingPhase 1NCT07139743
Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
Sponsor: Autolus Limited
Palo Alto, CA
RecruitingPhase 1NCT04699747
Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingPhase 1NCT03816345
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Sponsor: National Cancer Institute (NCI)
Birmingham, AL · Palo Alto, CA · Sacramento, CA · +48 more sites
RecruitingPhase 1NCT05539729
Vancomycin Study in Multiple Sclerosis (MS)
Sponsor: Icahn School of Medicine at Mount Sinai
New York, NY
RecruitingPhase 1NCT06680037
A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders
Sponsor: TG Therapeutics, Inc.
La Jolla, CA · Ann Arbor, MI · Omaha, NE · +5 more sites
RecruitingPhase 1NCT06999434
Exploring the Utility of [18F]3F4AP for Demyelination Imaging
Sponsor: Yale University
New Haven, CT
RecruitingPhase 1NCT07224373
An Open-label Study of AZD0120 in Adults With Multiple Sclerosis
Sponsor: AstraZeneca
Tucson, AZ · Aurora, CO · Washington D.C., DC · +6 more sites
RecruitingPhase 1NCT07295847
A Study of AZD0120 in Autoimmune Diseases
Sponsor: AstraZeneca
Tucson, AZ · Stanford, CA · Chicago, IL · +5 more sites
RecruitingPhase 1NCT05849467
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, MD
RecruitingPhase 1NCT03759522
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
Sponsor: University of Alabama at Birmingham
Birmingham, AL
RecruitingPhase 1NCT06665165
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Sponsor: Amylyx Pharmaceuticals Inc.
La Jolla, CA · Washington D.C., DC · Gainesville, FL · +7 more sites
RecruitingPhase 1NCT07221240
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis
Sponsor: PRG Science & Technology Co., Ltd.
Baltimore, MD
RecruitingPhase 1NCT06138132
A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis
Sponsor: Stanford University
Palo Alto, CA
Not yet recruitingPhase 1NCT07883590
A Study of LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS).
Sponsor: Eli Lilly and Company
San Francisco, CA · Aurora, CO · Kansas City, KS
Not yet recruitingPhase 1NCT07854483
C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard Therapy
Sponsor: AbelZeta Inc.
Gilbert, AZ
Not yet recruitingPhase 1NCT07270120
Senolytics for Secondary Progressive MS
Sponsor: Ohio State University
Columbus, OH
Not yet recruitingPhase 1NCT07221799
OER Glibenclamide for Neuropathic Pain in Multiple Sclerosis
Sponsor: University of Maryland, Baltimore
Baltimore, MD
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.