Clinical trials in Newport Beach, CA

60 recruiting studies have a site in or near Newport Beach, CA, California.

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RecruitingPhase 3NCT07190209

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

Sponsor: Sanofi

La Palma, CA · Long Beach, CA · Los Angeles, CA · +72 more sites

RecruitingPhase 1NCT07304154

Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment

Sponsor: Kite, A Gilead Company

Newport Beach, CA · Palo Alto, CA · +3 more sites

RecruitingPhase 3NCT07611110

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

Sponsor: AstraZeneca

Duarte, CA · Irvine, CA · Newport Beach, CA · +25 more sites

RecruitingPhase 2NCT07288034

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

Sponsor: City of Hope Medical Center

Corona, CA · Duarte, CA · Huntington Beach, CA · +10 more sites

RecruitingPhase 2NCT07610395

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

Sponsor: Altesa Biosciences, Inc.

Inglewood, CA · Newport Beach, CA · San Diego, CA · +34 more sites

RecruitingPhase not listedNCT07676565

Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study

Sponsor: Indiana University

Newport Beach, CA · San Francisco, CA · +15 more sites

RecruitingPhase 4NCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

Sponsor: Takeda

Escondido, CA · Murrieta, CA · +98 more sites

RecruitingPhase 3NCT06935370

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Sponsor: Boehringer Ingelheim

Beverly Hills, CA · Covina, CA · Encinitas, CA · +86 more sites

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Beverly Hills, CA · Covina, CA · Encinitas, CA · +163 more sites

RecruitingPhase 3NCT06966700

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Sponsor: Merck Sharp & Dohme LLC

Burbank, CA · Clovis, CA · Fullerton, CA · +61 more sites

RecruitingPhase 2NCT06977581

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

Sponsor: Pfizer

Lancaster, CA · Newport Beach, CA · Northridge, CA · +33 more sites

RecruitingPhase 3NCT07225504

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Sponsor: Novartis Pharmaceuticals

Fullerton, CA · Newport Beach, CA · West Hollywood, CA · +40 more sites

RecruitingPhase not listedNCT07556159

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

Sponsor: Sanofi

California City, CA · La Palma, CA · Los Angeles, CA · +60 more sites

RecruitingPhase 3NCT07174336

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Sponsor: Eli Lilly and Company

Clovis, CA · Duarte, CA · Emeryville, CA · +126 more sites

RecruitingPhase 2NCT07219173

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

Sponsor: Eli Lilly and Company

Newport Beach, CA · Northridge, CA · Rolling Hills Estates, CA · +14 more sites

RecruitingPhase 2NCT07745361

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

Sponsor: Monte Rosa Therapeutics, Inc

Los Angeles, CA · Newport Beach, CA · +12 more sites

RecruitingPhase 2NCT07759245

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

Sponsor: Eli Lilly and Company

Newport Beach, CA · San Diego, CA · +16 more sites

RecruitingPhase 3NCT06216301

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

Sponsor: NovoCure GmbH

Fullerton, CA · Newport Beach, CA · Sacramento, CA · +35 more sites

RecruitingPhase 3NCT06959095

Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation

Sponsor: GlaxoSmithKline

Bakersfield, CA · Modesto, CA · Newport Beach, CA · +39 more sites

RecruitingPhase 2 / Phase 3NCT07005102

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Sponsor: AbbVie

Duarte, CA · Irvine, CA · Los Angeles, CA · +15 more sites

RecruitingPhase 1NCT07544589

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

Sponsor: Dispatch Biotherapeutics

Duarte, CA · Newport Beach, CA · +5 more sites

RecruitingPhase 3NCT06283966

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Sponsor: AstraZeneca

Apple Valley, CA · Canoga Park, CA · Castroville, CA · +232 more sites

RecruitingPhase 1 / Phase 2NCT06362252

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Sponsor: Daiichi Sankyo

Los Angeles, CA · Newport Beach, CA · +24 more sites

RecruitingPhase 1NCT05877599

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Sponsor: AstraZeneca

Duarte, CA · Los Angeles, CA · Newport Beach, CA · +17 more sites

RecruitingPhase 2NCT06540833

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

Sponsor: Intra-Cellular Therapies, Inc.

Anaheim, CA · Los Alamitos, CA · Newport Beach, CA · +25 more sites

RecruitingPhase 2NCT06651567

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

Sponsor: Intra-Cellular Therapies, Inc.

Anaheim, CA · Costa Mesa, CA · Garden Grove, CA · +28 more sites

RecruitingPhase 3NCT06819891

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Lancaster, CA · Newport Beach, CA · Pomona, CA · +58 more sites

RecruitingPhase 1NCT06218914

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

Sponsor: AstraZeneca

Duarte, CA · Los Angeles, CA · Newport Beach, CA · +15 more sites

RecruitingPhase 2NCT06932263

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

Sponsor: AstraZeneca

Bakersfield, CA · Huntington Beach, CA · La Mesa, CA · +61 more sites

RecruitingPhase 2 / Phase 3NCT07196722

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Canoga Park, CA · Coronado, CA · +58 more sites

RecruitingPhase 3NCT07196748

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Coronado, CA · Lancaster, CA · +53 more sites

RecruitingPhase 3NCT07499232

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Lancaster, CA · Los Alamitos, CA · +36 more sites

RecruitingPhase 3NCT06357533

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Sponsor: AstraZeneca

Anaheim, CA · Beverly Hills, CA · Fountain Valley, CA · +60 more sites

RecruitingPhase not listedNCT06433752

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Sponsor: TG Therapeutics, Inc.

Fresno, CA · Newport Beach, CA · Orange, CA · +106 more sites

RecruitingPhase 3NCT07661329

A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension

Sponsor: YS Life Science Co., Ltd.

Beverly Hills, CA · Inglewood, CA · Newport Beach, CA · +11 more sites

RecruitingNot applicableNCT07355270

A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)

Sponsor: Aqua Medical, Inc.

Newport Beach, CA · +3 more sites

RecruitingPhase 4NCT06095128

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Sponsor: Takeda

Los Angeles, CA · Newport Beach, CA · +35 more sites

RecruitingNot applicableNCT07711691

Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)

Sponsor: University of California, Irvine

Anaheim, CA · Costa Mesa, CA · Irvine, CA · +54 more sites

RecruitingPhase 3NCT07793409

A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD)

Sponsor: Sanofi

Newport Beach, CA · +1 more sites

RecruitingPhase 3NCT07037459

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Sponsor: Amgen

Beverly Hills, CA · Covina, CA · Huntington Beach, CA · +118 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.