RightFit
RecruitingNot applicable

Penn Medicine Healthy Heart

Reducing Atherosclerotic Cardiovascular Disease (ASCVD) Through a Comprehensive Heart Disease Prevention Program (HDPP)

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
35 Years to 80 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests whether a program to change health habits can improve blood pressure and cholesterol over 6 months. It is for Penn Medicine patients in West/Southwest Philadelphia and Lancaster who have high blood pressure and meet other heart health rules.

To leverage access to patients across the primary care network, EPIC tools for identifying eligible patients, and the Way to Health platform to launch and enroll a program that will be evaluated in a clinical trial that is focused on changing patient behavior and powered to detect differences in improving blood pressure and cholesterol over 6 months for Penn Medicine patients in West/Southwest Philadelphia and Lancaster.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Be listed in the Penn Medicine primary care patient registry.
  • Have a top blood pressure number of 140 or higher on your last 2 readings from outpatient visits in the past 12 months.
  • Have at least one of these: heart or blood vessel disease from plaque buildup; a heart disease risk score of 10% or higher; diagnosed diabetes; an A1c of 6.5 or higher in the past year; a listing in the diabetes registry; or a most recent LDL of 190 or higher within the past 5 years. A1c measures average blood sugar. LDL is “bad” cholesterol.
  • Either take no statin, PCSK9 drug, or inclisiran, or take a low- or medium-strength statin with LDL above 100. These medicines lower cholesterol.

Who can't join

  • Take a PCSK9 inhibitor, a type of cholesterol medicine.
  • Have a statin allergy or trouble tolerating statins noted in your medical record.
  • Are pregnant.
  • Are breastfeeding.
  • Have a much shorter expected lifespan, including from cancer that has spread, hospice care, kidney failure, heart failure, or dementia. Heart failure means the heart does not pump well. Dementia affects memory and thinking.
  • Do not speak English and need a translator.
  • Do not have a cell phone.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * On the Penn Medicine Primary Care Service Line registry * Last 2 Blood Pressure readings with Systolic Blood Pressure \>=140 from any outpatient encounter in the last 12 months AND * ASCVD dx OR ASCVD risk score ≥10% OR Diabetes dx OR A1c ≥6.5 in last year OR Diabetes registry OR Last LDL ≥190 in past five years AND * Not on a statinor PCSK9, Inclisiran OR on a Low-intensity/moderate-intensity statin) with LDL \>100 Exclusion Criteria: * Patients on PCSK9 inhibitors * Documented statin allergy/ or intolerance in the EMR * Pregnancy * Breast feeding * Markedly shortened life expectancy including: 1. metastatic cancer 2. hospice 3. End Stage Renal Disease 4. Congestive Heart Failure 5. Dementia * Is a non-English speaker requiring a translator * Patients who do not have a cell phone

Study sites (1)

PA