RecruitingNot applicable

Antidepressant Adherence for Depressed Adults in Primary Care

Antidepressant Medication Adherence in Adults With Depression

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
21 Years to 64 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Pills

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Participants in the study will be given a special pill bottle for depression medication."
  • "This pill bottle will track how often the bottle is opened to take medication and it will transmit that information to the research team."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Official eligibility criteria

Inclusion Criteria: * Penn Medicine primary care outpatients * Clinical diagnosis of major depressive disorder * A score of 10+ on the Patient Health Questionnaire 9 (PHQ-9) * Age 21 to 64 years at the time of study entry * Prescribed an antidepressant by their primary care clinician * Express interest in taking antidepressant medication * Own a cell phone * Capable of using the electronic pill bottle * English-speaking Exclusion Criteria: * Treated with antidepressants in the past 90 days * Pregnant or breastfeeding * An active substance use disorder other than nicotine * A lifetime history of treatment for bipolar disorder or schizophrenia * Hospital admission or emergency department visit for suicidal symptoms in the past year * Lack capacity to provide informed consent * Using antidepressant more than 10 days at baseline assessment

Study sites (1)

PA