RightFit
RecruitingPhase 2

Study of EVO756 in Adults With Migraine

A Randomized, Double-Blind, Placebo Controlled Study Evaluating the Efficacy and Safety of EVO756 for the Prevention of Migraine in Adults

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years to 64 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests how well EVO756 works and how safe it is compared with a placebo, which has no active medicine. It is for adults ages 18 to 64 with migraine whose past treatments to prevent migraines did not work.

This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Age 18 to 64.
  • Have migraine that meets standard diagnosis rules, with or without aura (warning signs such as changes in vision).
  • Have tried treatments to prevent migraines that did not work.
  • Are not currently using treatment to prevent migraines.

Who can't join

  • Have trouble telling migraines apart from other headaches, or have another primary headache disorder.
  • Use certain medicines that are not allowed in the study.
  • Have major medical, mental health, brain or nerve, or heart or blood vessel problems, or important abnormal lab test results.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Key Inclusion Criteria: * Adults aged 18 to \<65 years * Migraine with or without aura, per ICHD-3 criteria * History of failure with prior preventive migraine treatments * Not currently using migraine preventive therapy Key Exclusion Criteria: * Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders * Use of certain medications * Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities

Study sites (33)

AZ

CA

CT

FL

GA

MA

MI

NC

NJ

NY

OH

SC

TN

TX

VA

WV