Clinical trials in Charleston, SC

151 recruiting studies have a site in or near Charleston, SC, South Carolina.

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Showing 40 of 151 studies

RecruitingPhase 3NCT06136650

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Sponsor: Merck Sharp & Dohme LLC

Charleston, SC · +62 more sites

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Charleston, SC · +39 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Bluffton, SC · Boiling Springs, SC · Charleston, SC · +1147 more sites

RecruitingPhase 3NCT05980949

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Charleston, SC · +147 more sites

RecruitingPhase 1NCT06179069

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Charleston, SC · +10 more sites

RecruitingPhase not listedNCT06297291

Global Paradise System US Post Approval Study

Sponsor: ReCor Medical, Inc.

Charleston, SC · Columbia, SC · Spartanburg, SC · +43 more sites

RecruitingNot applicableNCT06423430

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Sponsor: Abbott Medical Devices

Charleston, SC · +25 more sites

RecruitingPhase 3NCT06819878

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Charleston, SC · Greenville, SC · +93 more sites

RecruitingPhase not listedNCT07098858

The WiSE®-UP Study (The WiSE System Utilization & Performance Study)

Sponsor: EBR Systems, Inc.

Charleston, SC · +11 more sites

RecruitingPhase 3NCT07177352

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

Sponsor: Hoffmann-La Roche

Charleston, SC · Summerville, SC · +66 more sites

RecruitingPhase 3NCT07181109

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Sponsor: Alnylam Pharmaceuticals

Charleston, SC · Columbia, SC · Greenville, SC · +270 more sites

RecruitingPhase 3NCT05156398

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

Sponsor: Pfizer

Charleston, SC · Greenville, SC · +54 more sites

RecruitingPhase 2NCT06317649

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Boiling Springs, SC · Charleston, SC · Easley, SC · +222 more sites

RecruitingNot applicableNCT07701785

Superior Parietal iTBS for PD-MCI

Sponsor: Medical University of South Carolina

Charleston, SC

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Anderson, SC · Charleston, SC · +163 more sites

RecruitingPhase 3NCT06307665

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Sponsor: AstraZeneca

Charleston, SC · Rock Hill, SC · +118 more sites

RecruitingPhase 3NCT06736574

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Sponsor: Cytokinetics

Charleston, SC · +87 more sites

RecruitingPhase 3NCT06966700

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Sponsor: Merck Sharp & Dohme LLC

Charleston, SC · Greenville, SC · +62 more sites

RecruitingPhase 3NCT06989112

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Sponsor: AstraZeneca

Charleston, SC · +62 more sites

RecruitingPhase 3NCT07667803

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

Sponsor: AstraZeneca

Charleston, SC · Gaffney, SC · +54 more sites

RecruitingPhase 2NCT07795814

A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)

Sponsor: Edgewise Therapeutics, Inc.

Charleston, SC · +27 more sites

RecruitingPhase 2NCT06031688

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Sponsor: SWOG Cancer Research Network

Anderson, SC · Charleston, SC · +276 more sites

RecruitingPhase 3NCT06405087

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Sponsor: Takeda

Charleston, SC · +12 more sites

RecruitingNot applicableNCT06911632

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

Sponsor: Tempus AI

Charleston, SC · +39 more sites

RecruitingPhase 3NCT03678025

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Sponsor: SWOG Cancer Research Network

Boiling Springs, SC · Charleston, SC · Greenville, SC · +331 more sites

RecruitingPhase not listedNCT06960096

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

Sponsor: Medical University of South Carolina

Charleston, SC

RecruitingPhase 2NCT06996652

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

Sponsor: Yale University

Charleston, SC · +17 more sites

RecruitingPhase 3NCT07174336

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Sponsor: Eli Lilly and Company

Charleston, SC · +128 more sites

RecruitingPhase 2NCT07415044

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Sponsor: Eli Lilly and Company

Charleston, SC · +51 more sites

RecruitingPhase 3NCT06119581

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Sponsor: Eli Lilly and Company

Charleston, SC · Greenville, SC · West Columbia, SC · +84 more sites

RecruitingPhase 3NCT06672549

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Sponsor: Eli Lilly and Company

Charleston, SC · +48 more sites

RecruitingPhase not listedNCT07143669

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

Sponsor: Blueprint Medicines Corporation

Charleston, SC · +24 more sites

RecruitingNot applicableNCT07177846

LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer

Sponsor: Medical University of South Carolina

Charleston, SC

RecruitingPhase 1NCT04429542

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

Sponsor: Bicara Therapeutics

Charleston, SC · +14 more sites

RecruitingPhase 1 / Phase 2NCT06121297

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Sponsor: Cabaletta Bio

Charleston, SC · +20 more sites

RecruitingNot applicableNCT06812533

Alleviant ALLAY-HFrEF Study

Sponsor: Alleviant Medical, Inc.

Charleston, SC · +38 more sites

RecruitingNot applicableNCT03523416

Early Feasibility Study - Edwards APTURE Transcatheter Shunt System

Sponsor: Edwards Lifesciences

Charleston, SC · +18 more sites

RecruitingPhase 1 / Phase 2NCT04585750

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Sponsor: PMV Pharmaceuticals, Inc

Charleston, SC · +31 more sites

RecruitingPhase 3NCT06283966

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Sponsor: AstraZeneca

Anderson, SC · Charleston, SC · +232 more sites

RecruitingPhase 2NCT06680830

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Sponsor: Neuron23 Inc.

Charleston, SC · +44 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.