Clinical trials in Raleigh, NC

58 recruiting studies have a site in or near Raleigh, NC, North Carolina.

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Showing 40 of 58 studies

RecruitingPhase 3NCT07067463

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Sponsor: Zenas BioPharma (USA), LLC

Raleigh, NC · +18 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Asheboro, NC · +1147 more sites

RecruitingPhase 3NCT06498635

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI)

Cary, NC · Durham, NC · +278 more sites

RecruitingPhase 3NCT07513376

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

Sponsor: Merck Sharp & Dohme LLC

Asheville, NC · Chapel Hill, NC · Raleigh, NC · +21 more sites

RecruitingPhase not listedNCT06297291

Global Paradise System US Post Approval Study

Sponsor: ReCor Medical, Inc.

Chapel Hill, NC · Durham, NC · Raleigh, NC · +43 more sites

RecruitingPhase 3NCT07391774

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Sponsor: National Cancer Institute (NCI)

Cary, NC · Clinton, NC · Durham, NC · +200 more sites

RecruitingPhase 3NCT07674654

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

Sponsor: Kallyope Inc.

Charlotte, NC · Greensboro, NC · +110 more sites

RecruitingPhase 3NCT07028853

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Sponsor: Pfizer

Cary, NC · Durham, NC · +124 more sites

RecruitingPhase 3NCT07816367

A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

Sponsor: Kallyope Inc.

Cary, NC · Morehead City, NC · Raleigh, NC · +69 more sites

RecruitingNot applicableNCT06511141

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Sponsor: Axonics, Inc.

Raleigh, NC · +22 more sites

RecruitingPhase 3NCT07225504

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Sponsor: Novartis Pharmaceuticals

Charlotte, NC · Raleigh, NC · +41 more sites

RecruitingPhase 3NCT07325292

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

Sponsor: Sanofi

Charlotte, NC · Raleigh, NC · +32 more sites

RecruitingPhase 3NCT07667803

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

Sponsor: AstraZeneca

Greensboro, NC · Raleigh, NC · Rocky Mount, NC · +53 more sites

RecruitingPhase 2NCT07646613

Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients

Sponsor: Aspeya, Inc.

Raleigh, NC · +19 more sites

RecruitingPhase 2NCT06226883

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Fayetteville, NC · High Point, NC · Raleigh, NC · +22 more sites

RecruitingPhase 3NCT07037433

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Sponsor: Amgen

Charlotte, NC · Durham, NC · Greensboro, NC · +137 more sites

RecruitingPhase 3NCT07222800

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Sponsor: Pfizer

Cary, NC · Durham, NC · +251 more sites

RecruitingPhase 3NCT06997497

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Sponsor: Merck Sharp & Dohme LLC

Raleigh, NC · +47 more sites

RecruitingPhase 2NCT06808984

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Sponsor: Celgene

Charlotte, NC · Raleigh, NC · +58 more sites

RecruitingNot applicableNCT06812533

Alleviant ALLAY-HFrEF Study

Sponsor: Alleviant Medical, Inc.

Asheville, NC · Durham, NC · Raleigh, NC · +37 more sites

RecruitingPhase 3NCT06283966

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Sponsor: AstraZeneca

Fayetteville, NC · Greensboro, NC · Greenville, NC · +232 more sites

RecruitingPhase 2NCT07616128

Study of EVO756 in Adults With Migraine

Sponsor: Evommune, Inc.

Asheville, NC · Raleigh, NC · +31 more sites

RecruitingPhase 1 / Phase 2NCT06619990

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

Sponsor: Xencor, Inc.

Raleigh, NC · +29 more sites

RecruitingPhase 2NCT06651567

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

Sponsor: Intra-Cellular Therapies, Inc.

Raleigh, NC · +30 more sites

RecruitingPhase 3NCT06742723

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Sponsor: AstraZeneca

Greenville, NC · Hickory, NC · Jacksonville, NC · +130 more sites

RecruitingPhase 2NCT07840326

A Phase 2a Study of SUN-627 in Participants With Non-Active Secondary Progressive and Primary Progressive Multiple Sclerosis (SPMS/PPMS)

Sponsor: Sundance Biosciences, Inc.

Raleigh, NC · +2 more sites

RecruitingPhase 3NCT05863195

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Sponsor: ECOG-ACRIN Cancer Research Group

Durham, NC · Raleigh, NC · Winston-Salem, NC · +59 more sites

RecruitingNot applicableNCT06559891

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

Sponsor: SoniVie Inc.

Raleigh, NC · +33 more sites

RecruitingPhase not listedNCT06433752

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Sponsor: TG Therapeutics, Inc.

Charlotte, NC · New Bern, NC · Raleigh, NC · +106 more sites

RecruitingPhase 3NCT07184931

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Sanofi

Chapel Hill, NC · Charlotte, NC · Durham, NC · +122 more sites

RecruitingPhase 3NCT05877963

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

Sponsor: TG Therapeutics, Inc.

Charlotte, NC · Raleigh, NC · +39 more sites

RecruitingPhase 3NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Sponsor: Ascletis Pharma (China) Co., Limited

Charlotte, NC · Durham, NC · Greenville, NC · +81 more sites

RecruitingPhase 3NCT06677060

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Sponsor: AstraZeneca

Charlotte, NC · Durham, NC · Fayetteville, NC · +195 more sites

RecruitingPhase 2NCT07340320

A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

Sponsor: Corxel Pharmaceuticals

Raleigh, NC · +33 more sites

RecruitingPhase 1 / Phase 2NCT06783309

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Sponsor: COUR Pharmaceutical Development Company, Inc.

Durham, NC · Greenville, NC · Raleigh, NC · +42 more sites

RecruitingPhase 2NCT07804615

A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy

Sponsor: Vima Therapeutics

Raleigh, NC · +28 more sites

RecruitingPhase 3NCT07662213

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Sponsor: AstraZeneca

Durham, NC · Morehead City, NC · Raleigh, NC · +61 more sites

RecruitingPhase 3NCT05879926

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Sponsor: NRG Oncology

Albemarle, NC · Asheboro, NC · +1223 more sites

RecruitingPhase 3NCT07662135

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

Sponsor: AstraZeneca

Kinston, NC · Raleigh, NC · Winston-Salem, NC · +30 more sites

RecruitingPhase 3NCT07662109

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

Sponsor: AstraZeneca

Raleigh, NC · +39 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.