Clinical trials in Greenville, NC

50 recruiting studies have a site in or near Greenville, NC, North Carolina.

Top conditions here

All conditions

Showing 40 of 50 studies

RecruitingPhase 3NCT03150693

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Sponsor: Alliance for Clinical Trials in Oncology

Chapel Hill, NC · Durham, NC · Greenville, NC · +452 more sites

RecruitingPhase 2NCT06317662

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Sponsor: National Cancer Institute (NCI)

Chapel Hill, NC · Charlotte, NC · Durham, NC · +112 more sites

RecruitingPhase 2NCT05554393

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Charlotte, NC · Durham, NC · +172 more sites

RecruitingPhase 3NCT06439082

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Sponsor: Novartis Pharmaceuticals

Greenville, NC · Winston-Salem, NC · +15 more sites

RecruitingPhase 3NCT07181109

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Sponsor: Alnylam Pharmaceuticals

Durham, NC · Greenville, NC · High Point, NC · +270 more sites

RecruitingPhase 2NCT06317649

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Chapel Hill, NC · Charlotte, NC · Durham, NC · +222 more sites

RecruitingPhase 4NCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

Sponsor: Takeda

Charlotte, NC · Greenville, NC · Pinehurst, NC · +98 more sites

RecruitingPhase 3NCT07064473

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Sponsor: Boehringer Ingelheim

Cary, NC · Chapel Hill, NC · Greenville, NC · +205 more sites

RecruitingPhase 2NCT06672146

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Charlotte, NC · Durham, NC · Greenville, NC · +132 more sites

RecruitingPhase 1 / Phase 2NCT06546670

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Sponsor: Novartis Pharmaceuticals

Charlotte, NC · Greenville, NC · +7 more sites

RecruitingPhase not listedNCT07556159

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

Sponsor: Sanofi

Asheville, NC · Gastonia, NC · Greenville, NC · +60 more sites

RecruitingNot applicableNCT06374238

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

Sponsor: University of Pittsburgh

Durham, NC · Greenville, NC · +12 more sites

RecruitingPhase 2NCT06699849

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

Sponsor: CSL Behring

Greenville, NC · +19 more sites

RecruitingPhase 2NCT07415044

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

Sponsor: Eli Lilly and Company

Greenville, NC · Wilmington, NC · +50 more sites

RecruitingPhase not listedNCT06071377

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Sponsor: National Alliance for Sickle Cell Centers

Chapel Hill, NC · Durham, NC · Greenville, NC · +5 more sites

RecruitingPhase 1NCT07187973

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

Sponsor: Disc Medicine, Inc

Durham, NC · Greenville, NC · +9 more sites

RecruitingPhase 2NCT05673148

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Sponsor: Alliance for Clinical Trials in Oncology

Charlotte, NC · Concord, NC · Greenville, NC · +185 more sites

RecruitingPhase 3NCT06283966

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Sponsor: AstraZeneca

Fayetteville, NC · Greensboro, NC · Greenville, NC · +232 more sites

RecruitingPhase 3NCT07190222

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

Sponsor: Sanofi

Greenville, NC · Statesville, NC · Winston-Salem, NC · +73 more sites

RecruitingPhase 3NCT07564414

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

Sponsor: Novo Nordisk A/S

Greensboro, NC · Greenville, NC · Morehead City, NC · +96 more sites

RecruitingPhase 3NCT06742723

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Sponsor: AstraZeneca

Greenville, NC · Hickory, NC · Jacksonville, NC · +130 more sites

RecruitingPhase 3NCT06357533

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Sponsor: AstraZeneca

Greenville, NC · Salisbury, NC · +61 more sites

RecruitingPhase 3NCT06561386

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Sponsor: Bristol-Myers Squibb

Asheville, NC · Greenville, NC · +54 more sites

RecruitingPhase 3NCT06609226

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Sponsor: Novo Nordisk A/S

Charlotte, NC · Durham, NC · Greenville, NC · +36 more sites

RecruitingPhase 3NCT04293562

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Sponsor: Children's Oncology Group

Asheville, NC · Chapel Hill, NC · Charlotte, NC · +183 more sites

RecruitingPhase 3NCT06612268

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

Sponsor: Novo Nordisk A/S

Durham, NC · Greenville, NC · +47 more sites

RecruitingPhase 2NCT06824168

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

Sponsor: Daiichi Sankyo

Charlotte, NC · Greenville, NC · +13 more sites

RecruitingPhase 3NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Sponsor: Ascletis Pharma (China) Co., Limited

Charlotte, NC · Durham, NC · Greenville, NC · +81 more sites

RecruitingNot applicableNCT06319014

Physical Activity to Mitigate PreEclampsia Risk

Sponsor: East Carolina University

Greenville, NC

RecruitingPhase 1 / Phase 2NCT06783309

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Sponsor: COUR Pharmaceutical Development Company, Inc.

Durham, NC · Greenville, NC · Raleigh, NC · +42 more sites

RecruitingPhase 3NCT06008197

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Sponsor: Colorado Prevention Center

Greenville, NC · +81 more sites

RecruitingPhase 3NCT06024746

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

Sponsor: Colorado Prevention Center

Charlotte, NC · Greenville, NC · Morrisville, NC · +43 more sites

RecruitingPhase 3NCT05879926

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Sponsor: NRG Oncology

Albemarle, NC · Asheboro, NC · +1223 more sites

RecruitingPhase not listedNCT06388421

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Sponsor: United Therapeutics

Chapel Hill, NC · Durham, NC · Greensboro, NC · +67 more sites

RecruitingPhase 1 / Phase 2NCT04726241

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Sponsor: PedAL BCU, LLC

Asheville, NC · Chapel Hill, NC · Charlotte, NC · +161 more sites

RecruitingPhase 2 / Phase 3NCT05431088

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

Sponsor: Pfizer

Chapel Hill, NC · +43 more sites

RecruitingPhase 1 / Phase 2NCT06481306

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Sponsor: Bristol-Myers Squibb

Greenville, NC · +18 more sites

RecruitingPhase 3NCT07567001

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Sponsor: Novo Nordisk A/S

Apex, NC · Concord, NC · Durham, NC · +203 more sites

RecruitingPhase not listedNCT04398628

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

Sponsor: American Thrombosis and Hemostasis Network

Chapel Hill, NC · Charlotte, NC · Greenville, NC · +73 more sites

RecruitingPhase 3NCT05812807

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Sponsor: Alliance for Clinical Trials in Oncology

Albemarle, NC · Asheboro, NC · +825 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.