RightFit Trial Directory

Heart Failure clinical trials in Durham, NC

36 recruiting heart failure studies with a site in Durham, NC.

All trials in Durham, NC · All Heart Failure trials

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Chapel Hill, NC · Charlotte, NC · Durham, NC · +37 more sites

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Asheville, NC · Chapel Hill, NC · Charlotte, NC · +163 more sites

RecruitingPhase 3NCT06736574

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Sponsor: Cytokinetics

Cary, NC · Chapel Hill, NC · Durham, NC · +85 more sites

RecruitingNot applicableNCT06898515

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Sponsor: Reprieve Cardiovascular, Inc

Durham, NC · Greensboro, NC · Winston-Salem, NC · +32 more sites

RecruitingNot applicableNCT06965504

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

Sponsor: Abiomed Inc.

Charlotte, NC · Durham, NC · Winston-Salem, NC · +14 more sites

RecruitingNot applicableNCT06812533

Alleviant ALLAY-HFrEF Study

Sponsor: Alleviant Medical, Inc.

Asheville, NC · Durham, NC · Raleigh, NC · +37 more sites

RecruitingPhase 2NCT06979362

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

Sponsor: Novo Nordisk A/S

Durham, NC · +28 more sites

RecruitingNot applicableNCT07069738

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Sponsor: Boston Scientific Corporation

Charlotte, NC · Durham, NC · +40 more sites

RecruitingPhase not listedNCT07559903

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

Sponsor: Emory University

Charlotte, NC · Durham, NC · +15 more sites

RecruitingNot applicableNCT06174103

BiVACOR® Total Artificial Heart Early Feasibility Study

Sponsor: BiVACOR Inc.

Durham, NC · +3 more sites

RecruitingPhase 3NCT07761117

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

Sponsor: AstraZeneca

Chapel Hill, NC · Durham, NC · Greensboro, NC · +117 more sites

RecruitingPhase 3NCT07207811

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Sponsor: Novo Nordisk A/S

Durham, NC · +62 more sites

RecruitingNot applicableNCT04592445

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

Sponsor: Axon Therapies, Inc.

Durham, NC · +23 more sites

RecruitingPhase 3NCT07037459

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Sponsor: Amgen

Asheville, NC · Durham, NC · Lenoir, NC · +118 more sites

RecruitingPhase 3NCT06677060

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Sponsor: AstraZeneca

Charlotte, NC · Durham, NC · Fayetteville, NC · +195 more sites

RecruitingNot applicableNCT05677100

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Sponsor: Procyrion

Charlotte, NC · Durham, NC · Wilmington, NC · +46 more sites

RecruitingPhase not listedNCT04278404

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Sponsor: Duke University

Chapel Hill, NC · Durham, NC · +48 more sites

RecruitingPhase not listedNCT00271180

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Sponsor: Medtronic

Durham, NC · Raleigh, NC · +111 more sites

RecruitingPhase not listedNCT05489705

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Sponsor: Bristol-Myers Squibb

Charlotte, NC · Durham, NC · +58 more sites

RecruitingPhase 3NCT07567001

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Sponsor: Novo Nordisk A/S

Apex, NC · Concord, NC · Durham, NC · +203 more sites

RecruitingNot applicableNCT05685303

Alleviant ALLAY-HF Study

Sponsor: Alleviant Medical, Inc.

Asheville, NC · Durham, NC · Raleigh, NC · +53 more sites

RecruitingPhase 2NCT06080074

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Sponsor: Stanford University

Durham, NC · +4 more sites

RecruitingPhase 3NCT06056297

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Sponsor: X4 Pharmaceuticals

Durham, NC · +21 more sites

RecruitingNot applicableNCT07159269

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

Sponsor: Duke University

Durham, NC

RecruitingNot applicableNCT06733012

Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

Sponsor: Duke University

Durham, NC

RecruitingPhase 1NCT07219511

A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

Sponsor: Vasa Therapeutics

Durham, NC · Winston-Salem, NC · +19 more sites

RecruitingNot applicableNCT06895070

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

Sponsor: XVIVO Perfusion

Durham, NC · +13 more sites

RecruitingPhase 2NCT03383419

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

Sponsor: Baylor Research Institute

Durham, NC · +2 more sites

RecruitingNot applicableNCT05839067

Supporting Health in Veterans With Heart Failure

Sponsor: Florida State University

Durham, NC · +3 more sites

RecruitingNot applicableNCT07101289

Eat Well Heart Failure

Sponsor: Duke University

Durham, NC

RecruitingNot applicableNCT05327062

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

Sponsor: XSpline S.p.A.

Durham, NC · +3 more sites

RecruitingPhase 3NCT02901184

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Sponsor: Uppsala University

Charlotte, NC · Durham, NC · +36 more sites

RecruitingPhase 1NCT06061549

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction

Sponsor: Sardocor Corp.

Durham, NC · +1 more sites

Not yet recruitingPhase 4NCT07686692

IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency

Sponsor: Duke University

Durham, NC

Not yet recruitingNot applicableNCT07634419

Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress

Sponsor: Duke University

Durham, NC · +2 more sites

Not yet recruitingPhase not listedNCT07532369

Occlutech AFR Fontan Study

Sponsor: Occlutech International AB

Durham, NC · +6 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.