RecruitingPhase 1NCT07830758
Resmetirom in Patients With MASH and HFpEF
Sponsor: Madrigal Pharmaceuticals, Inc.
Peoria, AZ · Oxnard, CA · Fort Myers, FL · +2 more sites
Phase 1 Heart Failure clinical trials
19 recruiting Phase 1 heart failure studies in the US. What trial phases mean
Other phases
RecruitingPhase 1NCT07490054
Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure
Sponsor: Melana Yuzefpolskaya, MD
New York, NY
RecruitingPhase 1NCT07137338
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Sponsor: Rocket Pharmaceuticals Inc.
San Diego, CA · Rochester, MN · Charleston, SC
RecruitingPhase 1NCT07465653
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Sponsor: Novartis Pharmaceuticals
Bradenton, FL · Inverness, FL · Jacksonville, FL · +2 more sites
RecruitingPhase 1NCT02966665
: Vascular Function in Health and Disease
Sponsor: D. Walter Wray
Salt Lake City, UT
RecruitingPhase 1NCT07547540
A Study of LY3971297 in Participants With Heart Failure
Sponsor: Eli Lilly and Company
Detroit, MI · St Louis, MO · Chapel Hill, NC · +1 more sites
RecruitingPhase 1NCT05753059
Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
Sponsor: Yale University
New Haven, CT
RecruitingPhase 1NCT07172971
Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy
Sponsor: Vanderbilt University Medical Center
Nashville, TN
RecruitingPhase 1NCT06428097
Levothyroxine Supplementation for Heart Transplant Recipients
Sponsor: University of California, San Francisco
San Francisco, CA
RecruitingPhase 1NCT06770023
Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
Sponsor: Mayo Clinic
Jacksonville, FL
RecruitingPhase 1NCT06209359
Mechanisms of Diuretic Resistance in Heart Failure, Aim 3
Sponsor: Yale University
New Haven, CT
RecruitingPhase 1NCT06312748
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
Sponsor: VA Office of Research and Development
Salt Lake City, UT
RecruitingPhase 1NCT07219511
A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Sponsor: Vasa Therapeutics
Little Rock, AR · Huntington Beach, CA · Santa Maria, CA · +18 more sites
RecruitingPhase 1NCT05647213
Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease
Sponsor: HeartWorks, Inc.
Rochester, MN
RecruitingPhase 1NCT06831825
Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
Sponsor: Medley Therapeutics
Houston, TX
RecruitingPhase 1NCT06228924
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Sponsor: Tenaya Therapeutics
San Francisco, CA · Aurora, CO · Baltimore, MD · +4 more sites
RecruitingPhase 1NCT06061549
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Sponsor: Sardocor Corp.
Durham, NC · Dallas, TX
Not yet recruitingPhase 1NCT07856043
[11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction
Sponsor: Stony Brook University
Stony Brook, NY
Not yet recruitingPhase 1NCT07838649
Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced Cardiotoxicity
Sponsor: Washington University School of Medicine
St Louis, MO
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.