Phase 3 Heart Failure clinical trials

22 recruiting Phase 3 heart failure studies in the US. What trial phases mean

Other phases

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Duarte, CA · La Jolla, CA · Loma Linda, CA · +37 more sites

RecruitingPhase 3NCT07192952

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Sponsor: Bayer

Aurora, CO · Wilmington, DE · Gainesville, FL · +19 more sites

RecruitingPhase 3NCT06935370

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Sponsor: Boehringer Ingelheim

Beverly Hills, CA · Covina, CA · Encinitas, CA · +86 more sites

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Alexander City, AL · Birmingham, AL · Fairhope, AL · +163 more sites

RecruitingPhase 3NCT06736574

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Sponsor: Cytokinetics

Alexander City, AL · Birmingham, AL · Tucson, AZ · +85 more sites

RecruitingPhase 3NCT06929806

Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure

Sponsor: Pharmacosmos A/S

Pasadena, CA

RecruitingPhase 3NCT07221851

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

Sponsor: Ascendis Pharma A/S

Palo Alto, CA · Sacramento, CA · Aurora, CO · +20 more sites

RecruitingPhase 3NCT07761117

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

Sponsor: AstraZeneca

Fairhope, AL · Anchorage, AK · Gilbert, AZ · +117 more sites

RecruitingPhase 3NCT07207811

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Sponsor: Novo Nordisk A/S

Phoenix, AZ · La Jolla, CA · Los Angeles, CA · +60 more sites

RecruitingPhase 3NCT07037459

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Sponsor: Amgen

Birmingham, AL · Dothan, AL · Fairhope, AL · +118 more sites

RecruitingPhase 3NCT06677060

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Sponsor: AstraZeneca

Birmingham, AL · Centreville, AL · Fairhope, AL · +195 more sites

RecruitingPhase 3NCT06008197

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Sponsor: Colorado Prevention Center

Birmingham, AL · Fairhope, AL · Huntsville, AL · +79 more sites

RecruitingPhase 3NCT06024746

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

Sponsor: Colorado Prevention Center

Fairhope, AL · Phoenix, AZ · Chula Vista, CA · +43 more sites

RecruitingPhase 3NCT07567001

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Sponsor: Novo Nordisk A/S

Alexander City, AL · Birmingham, AL · Fairhope, AL · +203 more sites

RecruitingPhase 3NCT06056297

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Sponsor: X4 Pharmaceuticals

Phoenix, AZ · Irvine, CA · La Jolla, CA · +19 more sites

RecruitingPhase 3NCT06597006

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Sponsor: Novartis Pharmaceuticals

San Francisco, CA · Washington D.C., DC · St Louis, MO · +1 more sites

RecruitingPhase 3NCT06033950

A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

Sponsor: Colorado Prevention Center

Fairhope, AL · Phoenix, AZ · Yuma, AZ · +51 more sites

RecruitingPhase 3NCT06349941

Home-based Cardiac Rehabilitation in Heart Failure

Sponsor: University of Texas Southwestern Medical Center

Dallas, TX

RecruitingPhase 3NCT06597019

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Sponsor: Novartis Pharmaceuticals

San Francisco, CA · Washington D.C., DC · +8 more sites

RecruitingPhase 3NCT06217302

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Sponsor: Alessandro Doria

Stanford, CA · Aurora, CO · Orlando, FL · +10 more sites

RecruitingPhase 3NCT05150704

MYTHS - MYocarditis THerapy With Steroids

Sponsor: Niguarda Hospital

San Diego, CA · Houston, TX · Charlottesville, VA · +1 more sites

RecruitingPhase 3NCT02901184

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Sponsor: Uppsala University

Alexander City, AL · Birmingham, AL · Tucson, AZ · +35 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.