RecruitingPhase 2NCT07752979
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
Sponsor: AbbVie
Louisville, KY · +58 more sites
Clinical trials in Louisville, KY
125 recruiting studies have a site in or near Louisville, KY, Kentucky.
Top conditions here
- Obesity (16)
- Lung Cancer (15)
- Heart Failure (14)
- Hypertension (9)
- Crohn's Disease (9)
- Prostate Cancer (9)
- Leukemia (8)
- Breast Cancer (8)
All conditions
- Alzheimer's Disease
- Asthma
- Breast Cancer
- COPD
- Crohn's Disease
- Depression
- Type 1 Diabetes
- Type 2 Diabetes
- Heart Failure
- Hypertension
- Leukemia
- Lung Cancer
- Lupus
- Migraine
- Multiple Sclerosis
- Obesity
- Parkinson's Disease
- Prostate Cancer
- Psoriasis
- Rheumatoid Arthritis
- Schizophrenia
- Sickle Cell Disease
- Ulcerative Colitis
- Colorectal Cancer
Showing 40 of 125 studies
RecruitingPhase 3NCT04267848
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Sponsor: National Cancer Institute (NCI)
Bardstown, KY · Corbin, KY · +1147 more sites
RecruitingPhase 2NCT06317662
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Sponsor: National Cancer Institute (NCI)
Lexington, KY · Louisville, KY · +113 more sites
RecruitingPhase 2NCT05554393
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Sponsor: National Cancer Institute (NCI)
Lexington, KY · Louisville, KY · +172 more sites
RecruitingPhase 3NCT06819878
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Sponsor: Hoffmann-La Roche
Crestview Hills, KY · Louisville, KY · +93 more sites
RecruitingPhase not listedNCT07676565
Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study
Sponsor: Indiana University
Louisville, KY · +16 more sites
RecruitingPhase 1NCT03460977
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
Sponsor: Pfizer
Louisville, KY · +42 more sites
RecruitingPhase 3NCT06170788
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)
Sponsor: Merck Sharp & Dohme LLC
Louisville, KY · +14 more sites
RecruitingPhase 3NCT06439082
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Sponsor: Novartis Pharmaceuticals
Louisville, KY · +16 more sites
RecruitingPhase 3NCT06617325
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Sponsor: UCB Biopharma SRL
Louisville, KY · +62 more sites
RecruitingPhase 3NCT07424404
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Louisville, KY · +55 more sites
RecruitingPhase 2NCT07697456
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
Sponsor: AbbVie
Louisville, KY · +59 more sites
RecruitingPhase 3NCT07845500
A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity
Sponsor: Pfizer
Louisville, KY · +15 more sites
RecruitingPhase 2NCT06317649
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Sponsor: National Cancer Institute (NCI)
Lexington, KY · Louisville, KY · +222 more sites
RecruitingPhase 3NCT06307652
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Sponsor: AstraZeneca
Louisville, KY · +165 more sites
RecruitingPhase 3NCT06307665
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Sponsor: AstraZeneca
Louisville, KY · +118 more sites
RecruitingPhase 3NCT06430801
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Sponsor: Merck Sharp & Dohme LLC
Louisville, KY · +86 more sites
RecruitingPhase 2NCT06672146
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
Sponsor: National Cancer Institute (NCI)
Louisville, KY · +133 more sites
RecruitingNot applicableNCT06898515
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Sponsor: Reprieve Cardiovascular, Inc
Louisville, KY · +34 more sites
RecruitingPhase 3NCT07088068
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Sponsor: Sanofi
Louisville, KY · +33 more sites
RecruitingPhase 3NCT07116967
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Sponsor: Bristol-Myers Squibb
Bowling Green, KY · Louisville, KY · Owensboro, KY · +119 more sites
RecruitingPhase 3NCT07144280
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Sponsor: Pfizer
Louisville, KY · +238 more sites
RecruitingPhase 3NCT07351045
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Sponsor: Hoffmann-La Roche
Louisville, KY · +43 more sites
RecruitingPhase not listedNCT07428447
Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease
Sponsor: CND Life Sciences
Louisville, KY · +7 more sites
RecruitingPhase 3NCT07595549
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Sponsor: Pfizer
Louisville, KY · +33 more sites
RecruitingPhase 3NCT07667803
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Sponsor: AstraZeneca
Louisville, KY · +55 more sites
RecruitingPhase 2NCT06699849
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
Sponsor: CSL Behring
Louisville, KY · +19 more sites
RecruitingPhase 3NCT07037433
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Sponsor: Amgen
Louisville, KY · +139 more sites
RecruitingPhase 2NCT07186101
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Sponsor: Eli Lilly and Company
Louisville, KY · +39 more sites
RecruitingPhase 3NCT07222137
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Sponsor: Eli Lilly and Company
Louisville, KY · +6 more sites
RecruitingPhase 3NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Sponsor: Pfizer
Elizabethtown, KY · Frankfort, KY · Lexington, KY · +251 more sites
RecruitingPhase 2NCT07415044
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Sponsor: Eli Lilly and Company
Louisville, KY · +51 more sites
RecruitingPhase 2NCT07589608
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Sponsor: Eli Lilly and Company
Louisville, KY · +39 more sites
RecruitingPhase 3NCT07794579
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Sponsor: Eli Lilly and Company
Louisville, KY · +79 more sites
RecruitingPhase 2NCT06143956
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Sponsor: Eli Lilly and Company
Louisville, KY · +49 more sites
RecruitingPhase 1 / Phase 2NCT06469944
Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
Sponsor: Merck Sharp & Dohme LLC
Louisville, KY · +7 more sites
RecruitingPhase 3NCT06672549
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
Sponsor: Eli Lilly and Company
Louisville, KY · +49 more sites
RecruitingPhase 3NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Sponsor: Eli Lilly and Company
Louisville, KY · +36 more sites
RecruitingPhase 3NCT06937099
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Sponsor: Eli Lilly and Company
Louisville, KY · +34 more sites
RecruitingPhase 3NCT06997497
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Sponsor: Merck Sharp & Dohme LLC
Lexington, KY · Louisville, KY · +46 more sites
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.