Phase 2 Lung Cancer clinical trials

74 recruiting Phase 2 lung cancer studies in the US. What trial phases mean

Other phases

RecruitingPhase 2NCT06731907

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Sponsor: Merck Sharp & Dohme LLC

Lexington, KY · Baltimore, MD · Fargo, ND · +2 more sites

RecruitingPhase 2NCT07288034

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

Sponsor: City of Hope Medical Center

Goodyear, AZ · Corona, CA · Duarte, CA · +10 more sites

RecruitingPhase 2NCT07770100

Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)

Sponsor: Mark Bernard

Lexington, KY

RecruitingPhase 2NCT07322341

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

Sponsor: University of Washington

Seattle, WA

RecruitingPhase 2NCT07415005

Lorlatinib Plus Local Consolidation Therapy In ALK Positive Advanced Non-Small Cell Lung Cancer

Sponsor: M.D. Anderson Cancer Center

Houston, TX

RecruitingPhase 2NCT06031688

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Sponsor: SWOG Cancer Research Network

Daphne, AL · Fairhope, AL · Mobile, AL · +275 more sites

RecruitingPhase 2NCT07476287

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

Sponsor: Pfizer

Duarte, CA · Encinitas, CA · Irvine, CA · +20 more sites

RecruitingPhase 2NCT06780098

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

Sponsor: Merck Sharp & Dohme LLC

Lexington, KY · Baltimore, MD · Dallas, TX · +1 more sites

RecruitingPhase 2NCT05967689

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

Sponsor: Taiho Oncology, Inc.

Birmingham, AL · Duarte, CA · Boston, MA · +15 more sites

RecruitingPhase 2NCT06449313

Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features

Sponsor: Georgetown University

Washington D.C., DC · St Louis, MO · Charlottesville, VA

RecruitingPhase 2NCT07492680

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Sponsor: Bristol-Myers Squibb

San Francisco, CA · Aurora, CO · Atlanta, GA · +13 more sites

RecruitingPhase 2NCT06265285

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Sponsor: Mayo Clinic

Jacksonville, FL

RecruitingPhase 2NCT07293247

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

Sponsor: Alliance for Clinical Trials in Oncology

Jonesboro, AR · Los Angeles, CA · Parker, CO · +108 more sites

RecruitingPhase 2NCT06172478

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Sponsor: Daiichi Sankyo

Duarte, CA · New Haven, CT · Kissimmee, FL · +10 more sites

RecruitingPhase 2NCT04253964

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

Sponsor: Wake Forest University Health Sciences

Charlotte, NC · Winston-Salem, NC

RecruitingPhase 2NCT06693336

An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer

Sponsor: ToLymph Inc.

Rochester, MN

RecruitingPhase 2NCT05578326

Study of Trilaciclib and Lurbinectidin

Sponsor: UNC Lineberger Comprehensive Cancer Center

Lebanon, NH · Chapel Hill, NC

RecruitingPhase 2NCT06855771

A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab Brengitecan in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion or MTAP Loss (MountainTAP-9)

Sponsor: Bristol-Myers Squibb

Anchorage, AK · Boston, MA · Detroit, MI · +7 more sites

RecruitingPhase 2NCT04105270

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

Sponsor: Masonic Cancer Center, University of Minnesota

Phoenix, AZ · Brainerd, MN · Deer River, MN · +7 more sites

RecruitingPhase 2NCT07459634

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

Sponsor: Jazz Pharmaceuticals

Los Angeles, CA · Jacksonville, FL · Atlanta, GA · +2 more sites

RecruitingPhase 2NCT06008730

Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer

Sponsor: Emory University

Atlanta, GA

RecruitingPhase 2NCT07002034

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Sponsor: Reunion Neuroscience Inc

Birmingham, AL · Tucson, AZ · San Diego, CA · +29 more sites

RecruitingPhase 2NCT04899908

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Sponsor: Brigham and Women's Hospital

Boston, MA

RecruitingPhase 2NCT07130786

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

Sponsor: Ayal A. Aizer, MD

Boston, MA

RecruitingPhase 2NCT07132190

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

Sponsor: Ayal A. Aizer, MD

Boston, MA

RecruitingPhase 2NCT07252739

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

Sponsor: Merck Sharp & Dohme LLC

Clermont, FL · Fargo, ND · Sioux Falls, SD

RecruitingPhase 2NCT07718672

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

Sponsor: Roswell Park Cancer Institute

Buffalo, NY

RecruitingPhase 2NCT07098988

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

Sponsor: CatalYm GmbH

Birmingham, AL · Los Angeles, CA · New Haven, CT · +4 more sites

RecruitingPhase 2NCT05242965

A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer

Sponsor: University of Washington

Omaha, NE · Seattle, WA

RecruitingPhase 2NCT06902272

ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer

Sponsor: University of Miami

Miami, FL

RecruitingPhase 2NCT05705492

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

Sponsor: OHSU Knight Cancer Institute

Portland, OR

RecruitingPhase 2NCT07405190

Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLC

Sponsor: Massachusetts General Hospital

Boston, MA

RecruitingPhase 2NCT06695845

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Sponsor: Jazz Pharmaceuticals

Prescott, AZ · Littleton, CO · Fort Myers, FL · +14 more sites

RecruitingPhase 2NCT07452224

ILKN421H Plus Pembrolizumab in Advanced Non-Small Cell Lung Cancer

Sponsor: iLeukon Therapeutics, Inc.

Los Angeles, CA · Fort Worth, TX

RecruitingPhase 2NCT07423585

Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer

Sponsor: Asrar Alahmadi

Columbus, OH

RecruitingPhase 2NCT05570825

SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer

Sponsor: University of Washington

Seattle, WA

RecruitingPhase 2NCT05742607

IPH5201 and Durvalumab in Patients With Resectable Non-Small Cell Lung Cancer (MATISSE)

Sponsor: Innate Pharma

St. Petersburg, FL · Tampa, FL · Chicago, IL · +3 more sites

RecruitingPhase 2NCT06364917

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

Sponsor: University of Alabama at Birmingham

Birmingham, AL

RecruitingPhase 2NCT06463665

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

Sponsor: Genelux Corporation

Bullhead City, AZ · Clermont, FL · Coral Springs, FL · +12 more sites

RecruitingPhase 2NCT05642572

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Sponsor: SWOG Cancer Research Network

Daphne, AL · Fairhope, AL · Mobile, AL · +451 more sites

RecruitingPhase 2NCT06731413

Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC)

Sponsor: Virginia Commonwealth University

Richmond, VA · Tappahannock, VA

RecruitingPhase 2NCT06477419

A Study of Sacituzumab Govitecan in People With Mesothelioma

Sponsor: Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ · Middletown, NJ · Montvale, NJ · +4 more sites

RecruitingPhase 2NCT05726383

Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic Sarcoma

Sponsor: Hackensack Meridian Health

Hackensack, NJ · Houston, TX

RecruitingPhase 2NCT05800587

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Sponsor: Fox Chase Cancer Center

Philadelphia, PA

RecruitingPhase 2NCT06503146

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Sponsor: National Cancer Institute (NCI)

Bethesda, MD

RecruitingPhase 2NCT04067830

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Sponsor: Roswell Park Cancer Institute

Buffalo, NY

RecruitingPhase 2NCT05657873

A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

Sponsor: Memorial Sloan Kettering Cancer Center

Miami, FL · Basking Ridge, NJ · Middletown, NJ · +6 more sites

RecruitingPhase 2NCT05456256

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

Sponsor: Lantern Pharma Inc.

Beverly Hills, CA · Fountain Valley, CA · Los Alamitos, CA · +3 more sites

RecruitingPhase 2NCT05168566

Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer

Sponsor: Teligene US

Glendale, CA · Athens, GA · Louisville, KY · +3 more sites

RecruitingPhase 2NCT06841055

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

Sponsor: BioNTech SE

Birmingham, AL · Tampa, FL · Elizabethtown, KY · +2 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.