Clinical trials in Roanoke, VA

37 recruiting studies have a site in or near Roanoke, VA, Virginia.

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Showing 37 of 37 studies

RecruitingPhase 3NCT06136650

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Sponsor: Merck Sharp & Dohme LLC

Charlottesville, VA · Fairfax, VA · +60 more sites

RecruitingPhase 2NCT06317662

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Sponsor: National Cancer Institute (NCI)

Charlottesville, VA · Norfolk, VA · Richmond, VA · +112 more sites

RecruitingPhase 3NCT06819878

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Chesapeake, VA · Lansdowne Town Center, VA · Lynchburg, VA · +92 more sites

RecruitingPhase 4NCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

Sponsor: Takeda

Roanoke, VA · Suffolk, VA · Williamsburg, VA · +98 more sites

RecruitingPhase 3NCT06935370

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Sponsor: Boehringer Ingelheim

Manassas, VA · Roanoke, VA · +87 more sites

RecruitingPhase 3NCT07028853

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Sponsor: Pfizer

Blacksburg, VA · Charlottesville, VA · +124 more sites

RecruitingPhase 3NCT06312176

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Sponsor: Merck Sharp & Dohme LLC

Fairfax, VA · Midlothian, VA · Richmond, VA · +43 more sites

RecruitingPhase 3NCT06646276

A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Sponsor: Bristol-Myers Squibb

Roanoke, VA · +19 more sites

RecruitingPhase 3NCT06966700

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Sponsor: Merck Sharp & Dohme LLC

Midlothian, VA · Norfolk, VA · Roanoke, VA · +61 more sites

RecruitingPhase 3NCT07144280

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Sponsor: Pfizer

Blacksburg, VA · Low Moor, VA · Quinton, VA · +238 more sites

RecruitingPhase 3NCT06822738

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Sponsor: AbbVie

Charlottesville, VA · Roanoke, VA · +27 more sites

RecruitingPhase 2NCT07186101

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Sponsor: Eli Lilly and Company

Richmond, VA · Roanoke, VA · +37 more sites

RecruitingPhase 3NCT07222800

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Sponsor: Pfizer

Arlington, VA · Blacksburg, VA · Fairfax, VA · +251 more sites

RecruitingPhase 3NCT06937086

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Sponsor: Eli Lilly and Company

Roanoke, VA · +36 more sites

RecruitingPhase 1 / Phase 2NCT06428409

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

Sponsor: Merck Sharp & Dohme LLC

Roanoke, VA · +12 more sites

RecruitingNot applicableNCT06812533

Alleviant ALLAY-HFrEF Study

Sponsor: Alleviant Medical, Inc.

Roanoke, VA · +39 more sites

RecruitingPhase 3NCT07691970

Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment

Sponsor: AstraZeneca

Roanoke, VA · +14 more sites

RecruitingPhase 3NCT07668414

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

Sponsor: Novo Nordisk A/S

Richmond, VA · Roanoke, VA · +43 more sites

RecruitingPhase 3NCT07164443

A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

Sponsor: Janssen Research & Development, LLC

Fairfax, VA · Norfolk, VA · Roanoke, VA · +51 more sites

RecruitingPhase 3NCT07438496

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

Sponsor: Janssen Research & Development, LLC

Roanoke, VA · +37 more sites

RecruitingPhase 2 / Phase 3NCT06780670

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Sponsor: Novartis Pharmaceuticals

Fairfax, VA · Roanoke, VA · +33 more sites

RecruitingPhase 3NCT04293562

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Sponsor: Children's Oncology Group

Charlottesville, VA · Falls Church, VA · Norfolk, VA · +183 more sites

RecruitingPhase 3NCT07037459

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Sponsor: Amgen

Arlington, VA · Falls Church, VA · Manassas, VA · +118 more sites

RecruitingPhase 1 / Phase 2NCT04726241

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Sponsor: PedAL BCU, LLC

Charlottesville, VA · Falls Church, VA · Norfolk, VA · +161 more sites

RecruitingPhase not listedNCT05489705

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Sponsor: Bristol-Myers Squibb

Charlottesville, VA · Richmond, VA · Roanoke, VA · +57 more sites

RecruitingPhase 3NCT06748222

E-Mindfulness Approaches for Living After Breast Cancer

Sponsor: NRG Oncology

Alexandria, VA · Fairfax, VA · +378 more sites

RecruitingPhase 2NCT06991114

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Sponsor: Artiva Biotherapeutics, Inc.

Roanoke, VA · +30 more sites

RecruitingPhase 1 / Phase 2NCT03526835

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Sponsor: Merus B.V.

Roanoke, VA · +30 more sites

RecruitingPhase 3NCT07196501

A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Sponsor: Neurocrine Biosciences

Roanoke, VA · +23 more sites

RecruitingPhase 2NCT06695845

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Sponsor: Jazz Pharmaceuticals

Roanoke, VA · +16 more sites

RecruitingNot applicableNCT03887715

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Sponsor: LivaNova

Roanoke, VA · +100 more sites

RecruitingPhase 3NCT05442567

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Sponsor: Takeda

Roanoke, VA · +21 more sites

RecruitingPhase 3NCT04779320

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Sponsor: Takeda

Roanoke, VA · +21 more sites

RecruitingPhase 2NCT06456593

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Sponsor: Abivax S.A.

Richmond, VA · Roanoke, VA · +41 more sites

RecruitingNot applicableNCT03142152

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Sponsor: Cardiac Dimensions, Inc.

Charlottesville, VA · Henrico, VA · Norfolk, VA · +72 more sites

RecruitingPhase 3NCT06435429

A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Sponsor: Jazz Pharmaceuticals

Fairfax, VA · Norfolk, VA · Roanoke, VA · +45 more sites

Not yet recruitingNot applicableNCT06458907

A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation.

Sponsor: P+F Products + Features USA Inc.

Charlottesville, VA · Norfolk, VA · Roanoke, VA · +31 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.