Clinical trials in Worcester, MA

64 recruiting studies have a site in or near Worcester, MA, Massachusetts.

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Showing 40 of 64 studies

RecruitingPhase 3NCT04047628

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Worcester, MA · +22 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Beverly, MA · Boston, MA · +1147 more sites

RecruitingPhase 2NCT06317662

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Sponsor: National Cancer Institute (NCI)

Boston, MA · Worcester, MA · +113 more sites

RecruitingPhase 3NCT06498635

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI)

Beverly, MA · Burlington, MA · Gloucester, MA · +278 more sites

RecruitingPhase 3NCT07185009

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Sanofi

Worcester, MA · +36 more sites

RecruitingPhase 3NCT06170788

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

Sponsor: Merck Sharp & Dohme LLC

Worcester, MA · +14 more sites

RecruitingPhase 3NCT07424404

A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Boston, MA · Lexington, MA · Worcester, MA · +53 more sites

RecruitingPhase 4NCT07609914

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

Sponsor: Pfizer

Worcester, MA · +20 more sites

RecruitingPhase 3NCT07729462

A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine

Sponsor: Pfizer

Worcester, MA · +18 more sites

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Boston, MA · Fall River, MA · Worcester, MA · +163 more sites

RecruitingPhase 2NCT06656416

ALTO-100 in Bipolar Disorder With Depression (BD-D)

Sponsor: Alto Neuroscience

Worcester, MA · +57 more sites

RecruitingPhase 3NCT06989112

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Sponsor: AstraZeneca

Boston, MA · Worcester, MA · +61 more sites

RecruitingPhase 3NCT07007312

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Sponsor: Kura Oncology, Inc.

Worcester, MA · +43 more sites

RecruitingPhase 3NCT07144280

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Sponsor: Pfizer

Worcester, MA · +240 more sites

RecruitingPhase 2NCT06031688

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Sponsor: SWOG Cancer Research Network

Burlington, MA · Worcester, MA · +276 more sites

RecruitingPhase 2NCT06052254

Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

Sponsor: Teikoku Pharma USA, Inc.

Springfield, MA · Worcester, MA · +8 more sites

RecruitingPhase 3NCT07011745

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease

Sponsor: Bristol-Myers Squibb

Worcester, MA · +41 more sites

RecruitingPhase 3NCT07174336

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Sponsor: Eli Lilly and Company

Boston, MA · Worcester, MA · +126 more sites

RecruitingPhase 3NCT07299019

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

Sponsor: Zenas BioPharma (USA), LLC

Boston, MA · Worcester, MA · +24 more sites

RecruitingPhase 2NCT07410507

A Study of Brenipatide in Adult Participants With Schizophrenia

Sponsor: Eli Lilly and Company

Belmont, MA · Watertown, MA · Worcester, MA · +29 more sites

RecruitingPhase 1 / Phase 2NCT06121297

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Sponsor: Cabaletta Bio

Boston, MA · +18 more sites

RecruitingNot applicableNCT07072039

Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation

Sponsor: University of Massachusetts, Worcester

Worcester, MA

RecruitingPhase 3NCT07288567

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

Sponsor: Bristol-Myers Squibb

Boston, MA · Worcester, MA · +18 more sites

RecruitingPhase 2NCT07284667

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

Sponsor: ACADIA Pharmaceuticals Inc.

Watertown, MA · Worcester, MA · +26 more sites

RecruitingNot applicableNCT07210255

SAINT in Postpartum Depression (PPD)

Sponsor: Magnus Medical

Worcester, MA · +3 more sites

RecruitingPhase 3NCT07761117

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

Sponsor: AstraZeneca

Boston, MA · New Bedford, MA · +117 more sites

RecruitingPhase 3NCT06742723

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Sponsor: AstraZeneca

Boston, MA · Braintree, MA · +130 more sites

RecruitingPhase 2NCT06932263

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

Sponsor: AstraZeneca

Worcester, MA · +63 more sites

RecruitingPhase 3NCT04692493

RA-PRO PRAGMATIC TRIAL

Sponsor: University of Alabama at Birmingham

Boston, MA · Worcester, MA · +46 more sites

RecruitingPhase 2 / Phase 3NCT05076175

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Sponsor: Bristol-Myers Squibb

Boston, MA · Springfield, MA · Worcester, MA · +33 more sites

RecruitingPhase 3NCT07184931

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Sanofi

Boston, MA · Worcester, MA · +123 more sites

RecruitingNot applicableNCT07779707

The Medically Tailored Groceries and Mental Health Study

Sponsor: University of Massachusetts, Worcester

Worcester, MA

RecruitingPhase 3NCT06767514

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

Sponsor: Summit Therapeutics

Boston, MA · Brighton, MA · Foxborough, MA · +94 more sites

RecruitingPhase 3NCT04293562

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Sponsor: Children's Oncology Group

Boston, MA · +183 more sites

RecruitingPhase 2NCT06824168

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

Sponsor: Daiichi Sankyo

Worcester, MA · +14 more sites

RecruitingPhase 2NCT07002034

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Sponsor: Reunion Neuroscience Inc

Boston, MA · Worcester, MA · +30 more sites

RecruitingPhase 3NCT07662135

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

Sponsor: AstraZeneca

Braintree, MA · New Bedford, MA · Worcester, MA · +30 more sites

RecruitingPhase 3NCT07184996

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Sanofi

Boston, MA · Worcester, MA · +116 more sites

RecruitingNot applicableNCT07359157

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

Sponsor: Massachusetts General Hospital

Worcester, MA

RecruitingNot applicableNCT05317585

Continuous Glucose Monitor Use in Pregnancy

Sponsor: University of Massachusetts, Worcester

Worcester, MA

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.