RecruitingPhase 3NCT06763328
Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
Sponsor: City of Hope Medical Center
Duarte, CA · La Jolla, CA · Riverside, CA
Phase 3 Breast Cancer clinical trials
24 recruiting Phase 3 breast cancer studies in the US. What trial phases mean
Other phases
RecruitingPhase 3NCT07391774
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
Sponsor: National Cancer Institute (NCI)
Jonesboro, AR · Auburn, CA · Berkeley, CA · +200 more sites
RecruitingPhase 3NCT06841354
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
Sponsor: Merck Sharp & Dohme LLC
Mobile, AL · Chandler, AZ · Duarte, CA · +36 more sites
RecruitingPhase 3NCT07174336
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Sponsor: Eli Lilly and Company
Anchorage, AK · Chandler, AZ · Phoenix, AZ · +126 more sites
RecruitingPhase 3NCT05774678
Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Tissue Nanomechanical Phenotype Evaluation
Sponsor: M.D. Anderson Cancer Center
Houston, TX
RecruitingPhase 3NCT06790693
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Sponsor: Hoffmann-La Roche
Goodyear, AZ · Phoenix, AZ · Burbank, CA · +59 more sites
RecruitingPhase 3NCT06982521
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
Sponsor: Relay Therapeutics, Inc.
Gilbert, AZ · Beverly Hills, CA · Duarte, CA · +49 more sites
RecruitingPhase 3NCT05646862
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
Sponsor: Hoffmann-La Roche
Greenbrae, CA · Los Alamitos, CA · Los Angeles, CA · +36 more sites
RecruitingPhase 3NCT06492616
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Sponsor: Stemline Therapeutics, Inc.
Daphne, AL · Chandler, AZ · Gilbert, AZ · +173 more sites
RecruitingPhase 3NCT05379153
Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial
Sponsor: Alliance for Clinical Trials in Oncology
Ann Arbor, MI · Columbus, OH
RecruitingPhase 3NCT05879926
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Sponsor: NRG Oncology
Birmingham, AL · Anchorage, AK · +1223 more sites
RecruitingPhase 3NCT06072612
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
Sponsor: BriaCell Therapeutics Corporation
Phoenix, AZ · Tucson, AZ · Anaheim, CA · +76 more sites
RecruitingPhase 3NCT05232916
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Sponsor: Greenwich LifeSciences, Inc.
Mobile, AL · Goodyear, AZ · Tucson, AZ · +48 more sites
RecruitingPhase 3NCT05812807
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Sponsor: Alliance for Clinical Trials in Oncology
Birmingham, AL · Fairhope, AL · Mobile, AL · +825 more sites
RecruitingPhase 3NCT06748222
E-Mindfulness Approaches for Living After Breast Cancer
Sponsor: NRG Oncology
Phoenix, AZ · Fort Smith, AR · Jonesboro, AR · +378 more sites
RecruitingPhase 3NCT05696626
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Sponsor: LeonaBio
Scottsdale, AZ · Tucson, AZ · Santa Rosa, CA · +33 more sites
RecruitingPhase 3NCT06960707
Two Versus One Week Breast Radiotherapy (RT)
Sponsor: Weill Medical College of Cornell University
New York, NY
RecruitingPhase 3NCT03011684
Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial
Sponsor: University of California, San Francisco
San Francisco, CA
RecruitingPhase 3NCT07357298
Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Miami, FL · Tampa, FL
RecruitingPhase 3NCT04852887
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Sponsor: NRG Oncology
Birmingham, AL · Mobile, AL · Kingman, AZ · +809 more sites
RecruitingPhase 3NCT06435429
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
Sponsor: Jazz Pharmaceuticals
Phoenix, AZ · Tucson, AZ · +45 more sites
RecruitingPhase 3NCT05929768
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Sponsor: SWOG Cancer Research Network
Birmingham, AL · Anchorage, AK · +952 more sites
Not yet recruitingPhase 3NCT07723469
Phase 3 Trial of SRG-514 Administered Intraoperatively to Patients Undergoing Breast-Conserving Surgery
Sponsor: SURGE Therapeutics
Rochester, MN · New York, NY · Durham, NC
Not yet recruitingPhase 3NCT07695948
Effects, Metabolic Mechanisms and Predictors of Response to Acupuncture in Treating Psychoneurological Symptoms Among Breast Cancer Survivors
Sponsor: University of Illinois at Chicago
Chicago, IL
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.