Phase 2 Breast Cancer clinical trials

77 recruiting Phase 2 breast cancer studies in the US. What trial phases mean

Other phases

RecruitingPhase 2NCT01174121

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Sponsor: National Cancer Institute (NCI)

Bethesda, MD

RecruitingPhase 2NCT06049355

EMBRACE: Exercising Together

Sponsor: OHSU Knight Cancer Institute

Portland, OR

RecruitingPhase 2NCT06749210

DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

Sponsor: Ohio State University Comprehensive Cancer Center

New Haven, CT · Columbus, OH

RecruitingPhase 2NCT05676255

The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project

Sponsor: University of Arizona

Tucson, AZ

RecruitingPhase 2NCT07405801

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

Sponsor: Hoffmann-La Roche

Anaheim, CA · Palo Alto, CA · Jacksonville, FL · +7 more sites

RecruitingPhase 2NCT02422641

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

Sponsor: Wake Forest University Health Sciences

Baltimore, MD · St Louis, MO · Winston-Salem, NC

RecruitingPhase 2NCT06153836

Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction

Sponsor: Mayo Clinic

Jacksonville, FL

RecruitingPhase 2NCT06760819

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Sponsor: Bayer

Birmingham, AL · Duarte, CA · Fort Myers, FL · +8 more sites

RecruitingPhase 2NCT05557877

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

Sponsor: Mayo Clinic

Scottsdale, AZ · Jacksonville, FL · Indianapolis, IN · +2 more sites

RecruitingPhase 2NCT06172478

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Sponsor: Daiichi Sankyo

Duarte, CA · New Haven, CT · Kissimmee, FL · +10 more sites

RecruitingPhase 2NCT06105684

Phase II Single Arm Trial of Low Dose Capecitabine in Patients With Advanced Breast Cancer

Sponsor: University of Alabama at Birmingham

Birmingham, AL

RecruitingPhase 2NCT07427394

Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer

Sponsor: AstraZeneca

St Louis, MO · East Providence, RI · Nashville, TN

RecruitingPhase 2NCT06179303

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Sponsor: University of Washington

St Louis, MO · Chapel Hill, NC · Seattle, WA

RecruitingPhase 2NCT06923527

Circulating Tumor DNA

Sponsor: Yale University

New Haven, CT · Washington D.C., DC · Baltimore, MD · +4 more sites

RecruitingPhase 2NCT07686250

Evaluation and Outcomes of SAVI Scout MD for Localized Breast Surgery

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Tampa, FL

RecruitingPhase 2NCT06797635

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

Sponsor: Merck Sharp & Dohme LLC

Santa Monica, CA · Skokie, IL · Billings, MT · +5 more sites

RecruitingPhase 2NCT04899908

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Sponsor: Brigham and Women's Hospital

Boston, MA

RecruitingPhase 2NCT04886531

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

Sponsor: Ruth O'Regan

Chicago, IL · Rochester, NY · Hershey, PA · +1 more sites

RecruitingPhase 2NCT05846789

Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers

Sponsor: Kathy Miller

Atlanta, GA · Carmel, IN · Indianapolis, IN · +4 more sites

RecruitingPhase 2NCT06902311

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

Sponsor: UNC Lineberger Comprehensive Cancer Center

Chapel Hill, NC

RecruitingPhase 2NCT05035836

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Sponsor: M.D. Anderson Cancer Center

Houston, TX

RecruitingPhase 2NCT07203378

Nurturing Exercise Routine for Greater Improvement in Zest and Energy on Enhertu

Sponsor: University of Utah

Salt Lake City, UT

RecruitingPhase 2NCT07459673

HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission

Sponsor: Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ · Middletown, NJ · Montvale, NJ · +4 more sites

RecruitingPhase 2NCT07776613

A Study of Romosozumab in People With Breast Cancer and Osteoporosis

Sponsor: Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ · Middletown, NJ · Montvale, NJ · +4 more sites

RecruitingPhase 2NCT05919108

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

Sponsor: Vanderbilt-Ingram Cancer Center

Atlanta, GA · Pittsburgh, PA · Nashville, TN · +2 more sites

RecruitingPhase 2NCT06263543

Sequencing Antibody Drug Conjugates in ER+/HER2 LOW/ULTRA LOW MBC

Sponsor: Reshma L. Mahtani, D.O.

Miami, FL · Atlanta, GA · Fairway, KS

RecruitingPhase 2NCT06525766

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

Sponsor: Mayo Clinic

Scottsdale, AZ

RecruitingPhase 2NCT06129747

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Sponsor: Case Comprehensive Cancer Center

Cleveland, OH

RecruitingPhase 2NCT06439693

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Sponsor: Dana-Farber Cancer Institute

Boston, MA

RecruitingPhase 2NCT06195306

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Sponsor: National Cancer Institute (NCI)

Kansas City, KS · Ann Arbor, MI · Columbus, OH

RecruitingPhase 2NCT07017673

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

Sponsor: Cedars-Sinai Medical Center

Los Angeles, CA · Pasadena, CA · +1 more sites

RecruitingPhase 2NCT07078604

A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer

Sponsor: University of Washington

Seattle, WA

RecruitingPhase 2NCT06184750

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Sponsor: National Cancer Institute (NCI)

Tucson, AZ · Chicago, IL · +8 more sites

RecruitingPhase 2NCT02896335

Palbociclib and Pembrolizumab In Central Nervous System Metastases

Sponsor: Massachusetts General Hospital

Boston, MA

RecruitingPhase 2NCT05595499

Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors

Sponsor: Jonsson Comprehensive Cancer Center

Alhambra, CA · Beverly Hills, CA · Burbank, CA · +4 more sites

RecruitingPhase 2NCT05467891

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

Sponsor: Oana Danciu

Birmingham, AL · Phoenix, AZ · Washington D.C., DC · +18 more sites

RecruitingPhase 2NCT06695845

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Sponsor: Jazz Pharmaceuticals

Prescott, AZ · Littleton, CO · Fort Myers, FL · +14 more sites

RecruitingPhase 2NCT07694986

Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Tampa, FL

RecruitingPhase 2NCT04614194

Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib

Sponsor: University of Texas Southwestern Medical Center

Dallas, TX

RecruitingPhase 2NCT05660083

Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

Sponsor: The Methodist Hospital Research Institute

Bethesda, MD · Houston, TX

RecruitingPhase 2NCT06917313

FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

Sponsor: Yale University

New Haven, CT · Columbus, OH

RecruitingPhase 2NCT06953882

Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy

Sponsor: Yale University

New Haven, CT

RecruitingPhase 2NCT07053085

A Study of Surgery and Radiotherapy in People With Breast Cancer

Sponsor: Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ · Middletown, NJ · Montvale, NJ · +4 more sites

RecruitingPhase 2NCT06727773

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

Sponsor: UNC Lineberger Comprehensive Cancer Center

Chapel Hill, NC

RecruitingPhase 2NCT07220135

Trial of Neoadjuvant THP vs TCHP for HER2-Amplified/Positive Breast Cancer

Sponsor: University of Kansas Medical Center

Fairway, KS · Kansas City, KS · Overland Park, KS · +5 more sites

RecruitingPhase 2NCT04434040

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

Sponsor: Dana-Farber Cancer Institute

San Francisco, CA · Chicago, IL · New Lenox, IL · +4 more sites

RecruitingPhase 2NCT07276880

Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer

Sponsor: UNC Lineberger Comprehensive Cancer Center

Chapel Hill, NC

RecruitingPhase 2NCT07443943

A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial

Sponsor: University of Michigan Rogel Cancer Center

Ann Arbor, MI

RecruitingPhase 2NCT07069595

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

Sponsor: UNC Lineberger Comprehensive Cancer Center

Chapel Hill, NC

RecruitingPhase 2NCT06042569

Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial

Sponsor: City of Hope Medical Center

Duarte, CA · Boston, MA · Rochester, NY

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.