RecruitingPhase 1 / Phase 2NCT06973564
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
Sponsor: Jacobio Pharmaceuticals Co., Ltd.
Cleveland, OH · +3 more sites
Colorectal Cancer clinical trials in Cleveland, OH
28 recruiting colorectal cancer studies with a site in Cleveland, OH.
RecruitingPhase 1 / Phase 2NCT05786924
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Sponsor: Institut de Recherches Internationales Servier
Cleveland, OH · +20 more sites
RecruitingPhase 1NCT07094204
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Sponsor: Astellas Pharma Inc
Cleveland, OH · +10 more sites
RecruitingPhase 3NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Sponsor: Pfizer
Cincinnati, OH · Cleveland, OH · Fairfield, OH · +251 more sites
RecruitingPhase 1 / Phase 2NCT05919264
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Sponsor: Parabilis Medicines, Inc.
Cleveland, OH · +29 more sites
RecruitingPhase 1 / Phase 2NCT06710756
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Sponsor: Perspective Therapeutics
Cleveland, OH · Columbus, OH · +14 more sites
RecruitingPhase 1NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Sponsor: Bicara Therapeutics
Cleveland, OH · +14 more sites
RecruitingPhase 3NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Sponsor: Summit Therapeutics
Akron, OH · Canton, OH · Cincinnati, OH · +109 more sites
RecruitingPhase 2NCT05673148
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
Sponsor: Alliance for Clinical Trials in Oncology
Centerville, OH · Cleveland, OH · +185 more sites
RecruitingPhase 2NCT06760819
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Sponsor: Bayer
Cleveland, OH · +10 more sites
RecruitingPhase 3NCT05863195
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
Sponsor: ECOG-ACRIN Cancer Research Group
Cleveland, OH · Columbus, OH · Youngstown, OH · +59 more sites
RecruitingNot applicableNCT07044362
Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis
Sponsor: Case Comprehensive Cancer Center
Cleveland, OH
RecruitingPhase 1NCT07217171
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
Sponsor: EvolveImmune United, Inc
Cleveland, OH · +15 more sites
RecruitingPhase not listedNCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Sponsor: Guardant Health, Inc.
Cincinnati, OH · Cleveland, OH · Toledo, OH · +30 more sites
RecruitingPhase 1 / Phase 2NCT06638502
Safety of HRX215 in Patients After Minor and Major Liver Resection
Sponsor: HepaRegeniX GmbH
Cleveland, OH · +3 more sites
RecruitingPhase 1NCT06586515
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Sponsor: Eli Lilly and Company
Cincinnati, OH · Cleveland, OH · +23 more sites
RecruitingPhase 2NCT06792695
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
Sponsor: AstraZeneca
Cleveland, OH · +13 more sites
RecruitingPhase 2NCT07425054
ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer
Sponsor: Jennifer Dorth
Cleveland, OH
RecruitingPhase 1 / Phase 2NCT03526835
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Sponsor: Merus B.V.
Cleveland, OH · Columbus, OH · Maumee, OH · +28 more sites
RecruitingPhase 1 / Phase 2NCT07079631
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
Sponsor: BioNTech SE
Cleveland, OH · +3 more sites
RecruitingPhase 1 / Phase 2NCT03947385
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Sponsor: IDEAYA Biosciences
Cincinnati, OH · Cleveland, OH · +10 more sites
RecruitingPhase 3NCT06950385
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Sponsor: Rapamycin Holdings Inc.
Cleveland, OH · Columbus, OH · +16 more sites
RecruitingNot applicableNCT06641310
Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
Sponsor: University of Michigan Rogel Cancer Center
Cleveland, OH · +1 more sites
RecruitingPhase 1NCT06720987
A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Sponsor: Kumquat Biosciences Inc.
Cleveland, OH · +10 more sites
RecruitingPhase not listedNCT04624555
The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
Sponsor: Case Comprehensive Cancer Center
Cleveland, OH
RecruitingPhase 1 / Phase 2NCT07030257
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
Sponsor: Tasca Therapeutics
Cleveland, OH · Maumee, OH · +11 more sites
RecruitingPhase 3NCT02000089
The Cancer of the Pancreas Screening-5 CAPS5)Study
Sponsor: Johns Hopkins University
Cleveland, OH · +8 more sites
RecruitingPhase 1 / Phase 2NCT05824975
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
Sponsor: GI Innovation, Inc.
Cleveland, OH · +4 more sites
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.