RightFit Trial Directory

Lung Cancer clinical trials in Philadelphia, PA

46 recruiting lung cancer studies with a site in Philadelphia, PA.

All trials in Philadelphia, PA · All Lung Cancer trials

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Philadelphia, PA · Pittsburgh, PA · +37 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Allentown, PA · Altoona, PA · Beaver, PA · +1147 more sites

RecruitingPhase 3NCT06498635

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI)

Allentown, PA · Bethlehem, PA · Bryn Mawr, PA · +278 more sites

RecruitingPhase 3NCT07513376

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

Sponsor: Merck Sharp & Dohme LLC

Philadelphia, PA · +23 more sites

RecruitingPhase 1 / Phase 2NCT04959175

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Sponsor: National Cancer Institute (NCI)

Philadelphia, PA · +1 more sites

RecruitingPhase 2NCT06731907

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Sponsor: Merck Sharp & Dohme LLC

Philadelphia, PA · +4 more sites

RecruitingPhase 1 / Phase 2NCT07038343

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Sponsor: Avenzo Therapeutics, Inc.

Philadelphia, PA · +18 more sites

RecruitingPhase 1 / Phase 2NCT07020221

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

Sponsor: Verastem, Inc.

Philadelphia, PA · +12 more sites

RecruitingPhase not listedNCT07871656

Lung Cancer Detection in Never Smokers Using Urine Volatile Organic Compound (VOCs)

Sponsor: Thomas Jefferson University

Philadelphia, PA

RecruitingPhase 2 / Phase 3NCT07100080

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Sponsor: Bristol-Myers Squibb

Philadelphia, PA · Pittsburgh, PA · +26 more sites

RecruitingPhase 3NCT06119581

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Sponsor: Eli Lilly and Company

Horsham, PA · Philadelphia, PA · Pittsburgh, PA · +84 more sites

RecruitingPhase 3NCT06216301

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

Sponsor: NovoCure GmbH

Philadelphia, PA · Pittsburgh, PA · +36 more sites

RecruitingPhase 1 / Phase 2NCT06362252

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Sponsor: Daiichi Sankyo

Lancaster, PA · Philadelphia, PA · +23 more sites

RecruitingPhase 1NCT07277413

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Sponsor: IDEAYA Biosciences

Philadelphia, PA · +22 more sites

RecruitingPhase 1NCT06218914

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

Sponsor: AstraZeneca

Philadelphia, PA · Pittsburgh, PA · +16 more sites

RecruitingPhase 1NCT07037758

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Sponsor: Amgen

Philadelphia, PA · Pittsburgh, PA · +11 more sites

RecruitingPhase not listedNCT07124000

DESTINY-PANTUMOUR04

Sponsor: AstraZeneca

Philadelphia, PA · +17 more sites

RecruitingPhase 3NCT06561386

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Sponsor: Bristol-Myers Squibb

Lancaster, PA · Philadelphia, PA · +54 more sites

RecruitingPhase 1NCT06858813

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

Sponsor: AbbVie

Philadelphia, PA · +9 more sites

RecruitingPhase 3NCT06767514

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

Sponsor: Summit Therapeutics

Philadelphia, PA · Pittsburgh, PA · +95 more sites

RecruitingPhase 2NCT07002034

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Sponsor: Reunion Neuroscience Inc

Philadelphia, PA · +31 more sites

RecruitingPhase 1NCT07217171

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

Sponsor: EvolveImmune United, Inc

Philadelphia, PA · +15 more sites

RecruitingPhase not listedNCT05059444

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Sponsor: Guardant Health, Inc.

Broomall, PA · Philadelphia, PA · York, PA · +30 more sites

RecruitingPhase 1 / Phase 2NCT06043817

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

Sponsor: Pierre Fabre Medicament

Philadelphia, PA · +8 more sites

RecruitingPhase 1NCT07027514

A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer

Sponsor: Ankyra Therapeutics, Inc

Philadelphia, PA · +10 more sites

RecruitingPhase 1NCT07216105

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Sponsor: Fate Therapeutics

Philadelphia, PA · +4 more sites

RecruitingPhase 1 / Phase 2NCT04165070

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Sponsor: Merck Sharp & Dohme LLC

Philadelphia, PA · +17 more sites

RecruitingNot applicableNCT04949464

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

Sponsor: AIDS Malignancy Consortium

Philadelphia, PA · +10 more sites

RecruitingPhase 1 / Phase 2NCT06706076

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

Sponsor: BlossomHill Therapeutics

Philadelphia, PA · +23 more sites

RecruitingPhase 1NCT06179160

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Sponsor: Incyte Corporation

Philadelphia, PA · +12 more sites

RecruitingPhase 1 / Phase 2NCT05098132

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

Sponsor: Synthekine

Philadelphia, PA · Pittsburgh, PA · +31 more sites

RecruitingPhase 3NCT06686771

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

Sponsor: Canadian Cancer Trials Group

Danville, PA · Hershey, PA · Lewisburg, PA · +68 more sites

RecruitingPhase 1NCT05568680

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Sponsor: Verismo Therapeutics

Philadelphia, PA · +4 more sites

RecruitingPhase 2NCT05642572

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Sponsor: SWOG Cancer Research Network

Altoona, PA · Beaver, PA · Butler, PA · +451 more sites

RecruitingPhase 2NCT05800587

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Sponsor: Fox Chase Cancer Center

Philadelphia, PA

RecruitingPhase 2 / Phase 3NCT03851445

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Sponsor: SWOG Cancer Research Network

Allentown, PA · Altoona, PA · Beaver, PA · +1226 more sites

RecruitingPhase 2NCT05456256

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

Sponsor: Lantern Pharma Inc.

Philadelphia, PA · +5 more sites

RecruitingPhase 2NCT07276789

Efficacy and Safety of a Single Dose of LS301-IT for Fluorescence Intraoperative Molecular Imaging (IMI) for Patients Undergoing Lung Cancer Resection for Non Small Cell Lung Cancer

Sponsor: Integro Theranostics

Philadelphia, PA · +1 more sites

RecruitingPhase 3NCT02468024

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

Sponsor: University of Texas Southwestern Medical Center

Philadelphia, PA · Pittsburgh, PA · +37 more sites

RecruitingPhase 1NCT05948865

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

Sponsor: Conjupro Biotherapeutics, Inc.

Philadelphia, PA · +10 more sites

RecruitingPhase 1 / Phase 2NCT06244771

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

Sponsor: Frontier Medicines Corporation

Philadelphia, PA · +14 more sites

RecruitingPhase not listedNCT06974981

Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Philadelphia, PA

RecruitingNot applicableNCT02984761

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Sponsor: VA Office of Research and Development

Philadelphia, PA · Pittsburgh, PA · +15 more sites

RecruitingPhase 1 / Phase 2NCT07030257

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

Sponsor: Tasca Therapeutics

Philadelphia, PA · +12 more sites

RecruitingNot applicableNCT05775939

PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial

Sponsor: Thomas Jefferson University

Philadelphia, PA

Not yet recruitingPhase 1NCT07650357

A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)

Sponsor: Clasp Therapeutics, Inc.

Philadelphia, PA · +3 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.