RecruitingPhase 1NCT07103018
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
Sponsor: K36 Therapeutics, Inc.
San Francisco, CA · Miami, FL · Port Saint Lucie, FL · +10 more sites
Phase 1 Prostate Cancer clinical trials
60 recruiting Phase 1 prostate cancer studies in the US. What trial phases mean
Other phases
RecruitingPhase 1NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Sponsor: Eli Lilly and Company
Duarte, CA · La Jolla, CA · Los Angeles, CA · +20 more sites
RecruitingPhase 1NCT06879041
A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
Sponsor: AstraZeneca
Palo Alto, CA · San Diego, CA · Miami, FL · +9 more sites
RecruitingPhase 1NCT03460977
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
Sponsor: Pfizer
Tucson, AZ · +42 more sites
RecruitingPhase 1NCT07824349
JUR-003 in Adult Patients With Metastatic Prostate Cancer
Sponsor: Juri Biosciences, Inc.
Grand Rapids, MI · Lake Success, NY · Nashville, TN · +1 more sites
RecruitingPhase 1NCT05997615
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
Sponsor: Astellas Pharma Global Development, Inc.
Duarte, CA · Irvine, CA · Orange, CA · +5 more sites
RecruitingPhase 1NCT07114601
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Sponsor: Eli Lilly and Company
Duarte, CA · Santa Monica, CA · Stanford, CA · +13 more sites
RecruitingPhase 1NCT05800665
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Sponsor: Genentech, Inc.
Scottsdale, AZ · New Haven, CT · Orlando, FL · +2 more sites
RecruitingPhase 1NCT06784193
Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors
Sponsor: Olema Pharmaceuticals, Inc.
Gilbert, AZ · Aurora, CO · Sarasota, FL · +10 more sites
RecruitingPhase 1NCT05176483
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Sponsor: Exelixis
Phoenix, AZ · Tucson, AZ · Palo Alto, CA · +43 more sites
RecruitingPhase 1NCT06095089
A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer
Sponsor: Janssen Research & Development, LLC
Aurora, CO · Atlanta, GA · Minneapolis, MN · +9 more sites
RecruitingPhase 1NCT05818683
A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer
Sponsor: Janssen Research & Development, LLC
Sarasota, FL · Grand Rapids, MI · St Louis, MO · +4 more sites
RecruitingPhase 1NCT06801236
Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
Sponsor: Acerand Therapeutics (Hong Kong) Limited
La Jolla, CA · Tampa, FL · Baltimore, MD · +5 more sites
RecruitingPhase 1NCT07082920
A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
Sponsor: Janssen Research & Development, LLC
Sarasota, FL · New York, NY · Cleveland, OH · +1 more sites
RecruitingPhase 1NCT07277270
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
Sponsor: GlaxoSmithKline
Reunion, FL · New Hyde Park, NY · Philadelphia, PA · +2 more sites
RecruitingPhase 1NCT07319871
A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
Sponsor: Janssen Research & Development, LLC
Sarasota, FL · New York, NY · Cleveland, OH
RecruitingPhase 1NCT07746713
A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer
Sponsor: Janssen Research & Development, LLC
Sarasota, FL · Grand Rapids, MI · West Valley City, UT
RecruitingPhase 1NCT07006727
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
Sponsor: Novartis Pharmaceuticals
Iowa City, IA · Boston, MA · Royal Oak, MI · +1 more sites
RecruitingPhase 1NCT05983432
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
Sponsor: SystImmune Inc.
Beverly Hills, CA · Duarte, CA · Orange, CA · +19 more sites
RecruitingPhase 1NCT07813637
Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC
Sponsor: Janux Therapeutics
Nashville, TN
RecruitingPhase 1NCT07080242
Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors
Sponsor: SystImmune Inc.
Huntsville, AL · Glendale, CA · Long Beach, CA · +21 more sites
RecruitingPhase 1NCT07493512
Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
Sponsor: Amgen
Denver, CO · +9 more sites
RecruitingPhase 1NCT07581184
A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer
Sponsor: Aktis Oncology, Inc.
Irvine, CA · Miami, FL · Kansas City, KS · +3 more sites
RecruitingPhase 1NCT06440005
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
Sponsor: Angiex, Inc.
Los Angeles, CA · Sarasota, FL · St Louis, MO · +4 more sites
RecruitingPhase 1NCT07545811
Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer
Sponsor: Janux Therapeutics
La Jolla, CA · St Louis, MO · Charleston, SC · +3 more sites
RecruitingPhase 1NCT06458712
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Sponsor: Duke Street Bio Ltd
Sacramento, CA · New Haven, CT · New York, NY · +1 more sites
RecruitingPhase 1NCT06582017
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
Sponsor: Nammi Therapeutics Inc
Los Angeles, CA · +7 more sites
RecruitingPhase 1NCT04221542
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
Sponsor: Amgen
Duarte, CA · Fullerton, CA · San Francisco, CA · +22 more sites
RecruitingPhase 1NCT05805371
PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer
Sponsor: City of Hope Medical Center
Duarte, CA
RecruitingPhase 1NCT06966024
Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
Sponsor: Deciphera Pharmaceuticals, LLC
Boston, MA · Ann Arbor, MI · St Louis, MO · +5 more sites
RecruitingPhase 1NCT06242470
A Study of MGC026 in Participants With Advanced Solid Tumors
Sponsor: MacroGenics
Los Angeles, CA · Grand Rapids, MI · Lake Success, NY · +4 more sites
RecruitingPhase 1NCT06257693
Enzalutamide Implants (Enolen) in Patients With Prostate Cancer
Sponsor: Alessa Therapeutics Inc.
Fresno, CA · San Francisco, CA · Chicago, IL · +7 more sites
RecruitingPhase 1NCT06067841
A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
Sponsor: Bristol-Myers Squibb
Palo Alto, CA · Sarasota, FL · Boston, MA · +5 more sites
RecruitingPhase 1NCT06910657
IDOV-Immune for Advanced Solid Tumors
Sponsor: ViroMissile, Inc.
St Louis, MO · Houston, TX · San Antonio, TX
RecruitingPhase 1NCT06545942
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
Sponsor: MOMA Therapeutics
Goodyear, AZ · La Jolla, CA · San Francisco, CA · +9 more sites
RecruitingPhase 1NCT06168487
Telmisartan in Prostate Cancer
Sponsor: Tyler J Curiel
Lebanon, NH
RecruitingPhase 1NCT05413421
Study of ORIC-944 in Patients With Metastatic Prostate Cancer
Sponsor: ORIC Pharmaceuticals
Colorado Springs, CO · Plantation, FL · Arlington Heights, IL · +17 more sites
RecruitingPhase 1NCT06217822
First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
Sponsor: Bayer
Duarte, CA · Minneapolis, MN · Omaha, NE · +1 more sites
RecruitingPhase 1NCT07503808
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
Sponsor: IDEAYA Biosciences
Denver, CO · Sarasota, FL · Detroit, MI · +12 more sites
RecruitingPhase 1NCT07540572
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors
Sponsor: IDEAYA Biosciences
Plantation, FL · East Brunswick, NJ · Lake Success, NY · +8 more sites
RecruitingPhase 1NCT04886986
Phase I Study of 225Ac-J591 Plus 177Lu-PSMA Small Molecule for Progressive Metastatic Castration Resistant Prostate Cancer
Sponsor: Weill Medical College of Cornell University
Brooklyn, NY · New York, NY
RecruitingPhase 1NCT05283330
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
Sponsor: Orano Med Theranostics, SAS
Chicago, IL · Iowa City, IA · Lexington, KY · +5 more sites
RecruitingPhase 1NCT04167969
The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer
Sponsor: Memorial Sloan Kettering Cancer Center
New York, NY
RecruitingPhase 1NCT07145177
177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer
Sponsor: University of California, San Francisco
San Francisco, CA
RecruitingPhase 1NCT07189403
A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate Cancer
Sponsor: Daiichi Sankyo
Sarasota, FL · New York, NY · Providence, RI
RecruitingPhase 1NCT07244341
A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)
Sponsor: Daiichi Sankyo
La Jolla, CA · Boston, MA · Newton, MA · +6 more sites
RecruitingPhase 1NCT06673329
Brodalumab in the Treatment of Immune-Related Adverse Events
Sponsor: Brian Henick, MD
New York, NY
RecruitingPhase 1NCT06044857
PSMA PET Response Guided SabR in High Risk Pca
Sponsor: University of Texas Southwestern Medical Center
Dallas, TX
RecruitingPhase 1NCT07424547
Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors
Sponsor: Conjupro Biotherapeutics, Inc.
Plantation, FL · Austin, TX · +2 more sites
RecruitingPhase 1NCT06193486
Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Tampa, FL
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.