Phase 3 Prostate Cancer clinical trials

29 recruiting Phase 3 prostate cancer studies in the US. What trial phases mean

Other phases

RecruitingPhase 3NCT06136650

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Sponsor: Merck Sharp & Dohme LLC

Tucson, AZ · Irvine, CA · Los Angeles, CA · +60 more sites

RecruitingPhase 3NCT07213674

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Sponsor: Amgen

Goodyear, AZ · Tucson, AZ · Duarte, CA · +43 more sites

RecruitingPhase 3NCT07611110

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

Sponsor: AstraZeneca

Dothan, AL · Phoenix, AZ · Duarte, CA · +25 more sites

RecruitingPhase 3NCT07365995

A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer

Sponsor: BioNTech SE

Santa Barbara, CA · Aurora, CO · Fort Myers, FL · +18 more sites

RecruitingPhase 3NCT06629779

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Sponsor: Pfizer

Chandler, AZ · Gilbert, AZ · Glendale, AZ · +36 more sites

RecruitingPhase 3NCT07028853

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Sponsor: Pfizer

Huntsville, AL · Chandler, AZ · +124 more sites

RecruitingPhase 3NCT03678025

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Sponsor: SWOG Cancer Research Network

Gilbert, AZ · Phoenix, AZ · +331 more sites

RecruitingPhase 3NCT07723248

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

Sponsor: ORIC Pharmaceuticals

Coral Springs, FL · Jeffersonville, IN · Holland, MI · +8 more sites

RecruitingPhase 3NCT06625034

Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer

Sponsor: Mayo Clinic

Scottsdale, AZ · Jacksonville, FL

RecruitingPhase 3NCT07200830

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Sponsor: Alliance for Clinical Trials in Oncology

Anchorage, AK · Bakersfield, CA · Irvine, CA · +135 more sites

RecruitingPhase 3NCT06626022

Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.

Sponsor: University of Alberta

Los Angeles, CA · Dallas, TX

RecruitingPhase 3NCT07164443

A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

Sponsor: Janssen Research & Development, LLC

La Jolla, CA · Los Angeles, CA · +51 more sites

RecruitingPhase 3NCT07225946

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

Sponsor: Janssen Research & Development, LLC

Chandler, AZ · Little Rock, AR · Fountain Valley, CA · +56 more sites

RecruitingPhase 3NCT05939414

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Sponsor: Novartis Pharmaceuticals

Fayetteville, AR · Los Angeles, CA · Palo Alto, CA · +36 more sites

RecruitingPhase 3NCT07548164

Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer

Sponsor: Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ · Middletown, NJ · Montvale, NJ · +5 more sites

RecruitingPhase 3NCT06986083

A Study of Changes to Prostate Procedures

Sponsor: Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ · Middletown, NJ · Montvale, NJ · +4 more sites

RecruitingPhase 3NCT06056830

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Sponsor: Clarity Pharmaceuticals Ltd

Birmingham, AL · Phoenix, AZ · Little Rock, AR · +26 more sites

RecruitingPhase 3NCT04423211

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Sponsor: ECOG-ACRIN Cancer Research Group

Anchorage, AK · +338 more sites

RecruitingPhase 3NCT07052214

PSMA PET Combined With MRI for the Detection of PCa

Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited

Los Angeles, CA · San Francisco, CA · Boca Raton, FL · +13 more sites

RecruitingPhase 3NCT06274047

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Sponsor: M.D. Anderson Cancer Center

Gilbert, AZ · Chicago, IL · Kansas City, KS · +3 more sites

RecruitingPhase 3NCT06520345

The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)

Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited

Orange, CA · Miami, FL · Glen Burnie, MD · +6 more sites

RecruitingPhase 3NCT06592924

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Sponsor: Canadian Cancer Trials Group

Anchorage, AK · +371 more sites

RecruitingPhase 3NCT06112990

Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression

Sponsor: University of Utah

Salt Lake City, UT

RecruitingPhase 3NCT07427043

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

Sponsor: Brigham and Women's Hospital

Boston, MA

RecruitingPhase 3NCT02064673

Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

Sponsor: yair lotan

Dallas, TX

RecruitingPhase 3NCT06563388

Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial

Sponsor: Roswell Park Cancer Institute

Buffalo, NY

RecruitingPhase 3NCT06470243

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

Sponsor: SWOG Cancer Research Network

Fayetteville, AR · Rogers, AR · Springdale, AR · +171 more sites

RecruitingPhase 3NCT07293585

Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment

Sponsor: Jonsson Comprehensive Cancer Center

Los Angeles, CA

Not yet recruitingPhase 3NCT06024772

Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer

Sponsor: Thomas Jefferson University

Philadelphia, PA

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.