Phase 1 Sickle Cell Disease clinical trials

13 recruiting Phase 1 sickle cell disease studies in the US. What trial phases mean

Other phases

RecruitingPhase 1NCT06506461

Gene Editing For Sickle Cell Disease

Sponsor: St. Jude Children's Research Hospital

Memphis, TN

RecruitingPhase 1NCT05904093

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Bethesda, MD

RecruitingPhase 1NCT07187973

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

Sponsor: Disc Medicine, Inc

Birmingham, AL · San Francisco, CA · Atlanta, GA · +8 more sites

RecruitingPhase 1NCT04055818

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

Sponsor: EpiDestiny, Inc.

Chicago, IL

RecruitingPhase 1NCT07226219

Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

Sponsor: St. Jude Children's Research Hospital

Memphis, TN

RecruitingPhase 1NCT06442761

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

Sponsor: St. Jude Children's Research Hospital

Birmingham, AL · Bethesda, MD · Memphis, TN

RecruitingPhase 1NCT07566494

Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Bethesda, MD

RecruitingPhase 1NCT07015684

131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)

Sponsor: Columbia University

New York, NY

RecruitingPhase 1NCT03279094

Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease

Sponsor: City of Hope Medical Center

Duarte, CA

RecruitingPhase 1NCT06647979

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Sponsor: Daniel Bauer

Boston, MA

RecruitingPhase 1NCT01245179

Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease

Sponsor: Abdullah Kutlar

Augusta, GA

Not yet recruitingPhase 1NCT07799571

Buprenorphine for the Management of Pain in Children With Sickle Cell Disease

Sponsor: Natasha Archer

Boston, MA

Not yet recruitingPhase 1NCT07708350

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease

Sponsor: Daniel Bauer

Boston, MA

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.