Phase 1/2 Sickle Cell Disease clinical trials

14 recruiting Phase 1/2 sickle cell disease studies in the US. What trial phases mean

Other phases

RecruitingPhase 1 / Phase 2NCT07599176

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Bethesda, MD

RecruitingPhase 1 / Phase 2NCT06546670

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Sponsor: Novartis Pharmaceuticals

Birmingham, AL · Miami, FL · Boston, MA · +6 more sites

RecruitingPhase 1 / Phase 2NCT06481306

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Sponsor: Bristol-Myers Squibb

Birmingham, AL · La Jolla, CA · Oakland, CA · +16 more sites

RecruitingPhase 1 / Phase 2NCT03653338

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sponsor: Paul Szabolcs

Pittsburgh, PA

RecruitingPhase 1 / Phase 2NCT02447874

Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease

Sponsor: Emory University

Atlanta, GA

RecruitingPhase 1 / Phase 2NCT04819841

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

Sponsor: Kamau Therapeutics

Los Angeles, CA · Palo Alto, CA · St Louis, MO · +3 more sites

RecruitingPhase 1 / Phase 2NCT07252050

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

Sponsor: Arkansas Children's Hospital Research Institute

Aurora, CO · Atlanta, GA · New Orleans, LA · +1 more sites

RecruitingPhase 1 / Phase 2NCT03128996

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Sponsor: Washington University School of Medicine

New Haven, CT · Wilmington, DE · Grand Rapids, MI · +1 more sites

RecruitingPhase 1 / Phase 2NCT05685368

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Sponsor: Children's Hospital Los Angeles

Los Angeles, CA

RecruitingPhase 1 / Phase 2NCT04156893

RH Genotype Matched RBC Transfusions

Sponsor: Children's Hospital of Philadelphia

Philadelphia, PA

RecruitingPhase 1 / Phase 2NCT04774536

Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease

Sponsor: Mark Walters, MD

Los Angeles, CA · Oakland, CA

RecruitingPhase 1 / Phase 2NCT04008368

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Bethesda, MD

RecruitingPhase 1 / Phase 2NCT06930703

Cannabidiol in Sickle Cell Disease

Sponsor: Icahn School of Medicine at Mount Sinai

Manhattan, NY

Not yet recruitingPhase 1 / Phase 2NCT07648043

Feasibility and Acceptability of Amani

Sponsor: Massachusetts General Hospital

Boston, MA

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.