RecruitingPhase 1NCT07169630
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Sponsor: National Institute of Mental Health (NIMH)
Bethesda, MD
Ensayos clínicos de enfermedad de alzheimer
285 estudios buscan participantes en EE. UU.
La investigación sobre el Alzheimer incluye estudios tempranos de medicamentos, ensayos de prevención en personas con cambios leves de memoria y muchos estudios sin medicamentos sobre el cuidado, el sueño y las imágenes del cerebro. Muchos estudios piden que un acompañante —normalmente un familiar— asista a las visitas con el participante. Durante la evaluación inicial es común hacer pruebas de memoria y, en algunos estudios de medicamentos, escáneres cerebrales o una punción lumbar.
Mostrando 40 de 285 estudios (en inglés)
RecruitingPhase 2NCT07721467
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
Sponsor: National Institute on Aging (NIA)
Baltimore, MD
RecruitingPhase 3NCT05980949
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Homewood, AL · Chandler, AZ · +145 more sites
RecruitingPhase not listedNCT06566170
A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease
Sponsor: Eli Lilly and Company
Huntsville, AL
RecruitingPhase not listedNCT07099053
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
Sponsor: National Institute on Aging (NIA)
Baltimore, MD
RecruitingPhase not listedNCT03019757
Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
Sponsor: Douglas Scharre
Columbus, OH
RecruitingPhase 3NCT07011732
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Sponsor: Bristol-Myers Squibb
Scottsdale, AZ · Anaheim, CA · Fresno, CA · +38 more sites
RecruitingPhase 3NCT07177352
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Sponsor: Hoffmann-La Roche
Birmingham, AL · Phoenix, AZ · Sun City, AZ · +65 more sites
RecruitingNot applicableNCT07866768
CMN LIFU for Enhanced Glymphatic Clearance in Amyloid-Positive MCI
Sponsor: University of California, San Francisco
San Francisco, CA
RecruitingPhase 2NCT07236190
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingNot applicableNCT07346183
CommunityRx-Dementia + Peer Navigation (CRxDpeer)
Sponsor: University of Chicago
Chicago, IL
RecruitingPhase 2NCT07636811
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Sponsor: Alnylam Pharmaceuticals
Maitland, FL · Naples, FL · Indianapolis, IN · +1 more sites
RecruitingPhase 3NCT07717411
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Sponsor: Hoffmann-La Roche
Irvine, CA · Long Beach, CA · Oakland, CA · +9 more sites
RecruitingPhase 2NCT06052254
Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type
Sponsor: Teikoku Pharma USA, Inc.
Chino, CA · Daytona Beach, FL · Delray Beach, FL · +7 more sites
RecruitingPhase 3NCT06976203
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Sponsor: Bristol-Myers Squibb
Fullerton, CA · Irvine, CA · Los Angeles, CA · +28 more sites
RecruitingPhase 3NCT07011745
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Sponsor: Bristol-Myers Squibb
Chandler, AZ · +39 more sites
RecruitingPhase 2NCT07033494
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Sponsor: Merck Sharp & Dohme LLC
Irvine, CA · Long Beach, CA · Los Angeles, CA · +33 more sites
RecruitingNot applicableNCT07216716
Evaluating the Effectiveness of the Health App Recommendation Tool
Sponsor: University of Pittsburgh
Pittsburgh, PA
RecruitingPhase 2NCT07589595
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Sponsor: Eli Lilly and Company
Chandler, AZ · Scottsdale, AZ · Carlsbad, CA · +39 more sites
RecruitingPhase 1NCT07787169
A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
Sponsor: Eli Lilly and Company
Anaheim, CA · Irvine, CA · Los Alamitos, CA · +10 more sites
RecruitingPhase 2NCT06847321
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Sponsor: Lighthouse Pharmaceuticals, Inc.
Phoenix, AZ · Scottsdale, AZ · +36 more sites
RecruitingPhase 2NCT06808984
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Sponsor: Celgene
Homewood, AL · Huntsville, AL · Phoenix, AZ · +57 more sites
RecruitingPhase 3NCT06976216
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Sponsor: Bristol-Myers Squibb
Long Beach, CA · Redlands, CA · Basalt, CO · +25 more sites
RecruitingNot applicableNCT07573982
Ultrasonic Debris Clearance to Promote Brain Resilience
Sponsor: Stanford University
Stanford, CA
RecruitingPhase not listedNCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Sponsor: Washington University School of Medicine
Jacksonville, FL · Indianapolis, IN · Boston, MA · +5 more sites
RecruitingNot applicableNCT05643144
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Sponsor: Indiana University
Indianapolis, IN
RecruitingNot applicableNCT07812337
Evaluation of a Decision-Support Tool for Blood Biomarker Testing for Alzheimer's Disease in Primary Care
Sponsor: University of Wisconsin, Madison
Madison, WI
RecruitingPhase 1 / Phase 2NCT06189963
Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
Sponsor: NKGen Biotech, Inc.
Glendale, CA · Santa Ana, CA · Tarzana, CA · +4 more sites
RecruitingNot applicableNCT07667478
NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE
Sponsor: Chi-Ying (Roy) Lin
Houston, TX
RecruitingPhase 2NCT06887192
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Sponsor: MapLight Therapeutics
Phoenix, AZ · Scottsdale, AZ · Tucson, AZ · +34 more sites
RecruitingPhase 2NCT06540833
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Sponsor: Intra-Cellular Therapies, Inc.
Anaheim, CA · Los Alamitos, CA · Newport Beach, CA · +25 more sites
RecruitingPhase 2NCT06651567
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Sponsor: Intra-Cellular Therapies, Inc.
Anaheim, CA · Costa Mesa, CA · Garden Grove, CA · +28 more sites
RecruitingPhase 1NCT07413744
The Gut - PRO Study
Sponsor: University of Wisconsin, Madison
Madison, WI
RecruitingNot applicableNCT03954899
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
Sponsor: Natalie Denburg
Iowa City, IA
RecruitingPhase 2NCT07794670
Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease
Sponsor: NewAmsterdam Pharma
Nashville, TN
RecruitingPhase 4NCT07633470
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Sponsor: Alpha Cognition, Inc
Irvine, CA · Orange, CA · Aventura, FL · +17 more sites
RecruitingPhase 1NCT07598370
A Study of LY3439539 in Participants With Alzheimer's Disease
Sponsor: Eli Lilly and Company
Irvine, CA · Long Beach, CA · Los Angeles, CA · +5 more sites
RecruitingPhase 1NCT07780383
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration
Sponsor: Bristol-Myers Squibb
Anaheim, CA · Bradenton, FL · Daytona Beach, FL · +3 more sites
RecruitingNot applicableNCT04855630
Combating Alzheimer's Through Sleep and Exercise
Sponsor: University of Miami
Miami, FL
RecruitingNot applicableNCT06094192
Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation
Sponsor: Boston University Charles River Campus
Boston, MA
La información proviene de ClinicalTrials.gov y es solo informativa; no es consejo médico. Confirme siempre su elegibilidad con el equipo del estudio y hable con su médico antes de tomar decisiones sobre su atención.