Clinical trials in Columbia, MO

49 recruiting studies have a site in or near Columbia, MO, Missouri.

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RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Ballwin, MO · Bolivar, MO · Branson, MO · +1147 more sites

RecruitingPhase 3NCT06623422

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Sponsor: Merck Sharp & Dohme LLC

Columbia, MO · Osage Beach, MO · +52 more sites

RecruitingPhase 2 / Phase 3NCT06712316

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

Sponsor: BioNTech SE

Columbia, MO · Fenton, MO · +51 more sites

RecruitingPhase 3NCT07424404

A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Columbia, MO · Saint Charles, MO · +54 more sites

RecruitingPhase 3NCT05156398

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

Sponsor: Pfizer

Columbia, MO · +53 more sites

RecruitingPhase 4NCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

Sponsor: Takeda

Bridgeton, MO · Columbia, MO · Kansas City, MO · +98 more sites

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Columbia, MO · Kansas City, MO · +163 more sites

RecruitingPhase 3NCT07116967

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

Sponsor: Bristol-Myers Squibb

Columbia, MO · St Louis, MO · +120 more sites

RecruitingPhase 3NCT07144280

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Sponsor: Pfizer

Columbia, MO · +240 more sites

RecruitingPhase 2NCT07525375

A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma

Sponsor: AstraZeneca

Columbia, MO · +14 more sites

RecruitingPhase not listedNCT03551951

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

Sponsor: University of Missouri-Columbia

Columbia, MO

RecruitingPhase 3NCT03678025

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Sponsor: SWOG Cancer Research Network

Cape Girardeau, MO · City of Saint Peters, MO · +331 more sites

RecruitingPhase not listedNCT05334069

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Sponsor: Alliance for Clinical Trials in Oncology

Ballwin, MO · Bolivar, MO · Branson, MO · +744 more sites

RecruitingPhase 2NCT05673148

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Sponsor: Alliance for Clinical Trials in Oncology

Columbia, MO · Farmington, MO · Saint Joseph, MO · +185 more sites

RecruitingPhase 2NCT06632977

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Sponsor: Alliance for Clinical Trials in Oncology

City of Saint Peters, MO · Columbia, MO · Creve Coeur, MO · +105 more sites

RecruitingPhase 3NCT07190222

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

Sponsor: Sanofi

Columbia, MO · Hannibal, MO · St Louis, MO · +73 more sites

RecruitingPhase 3NCT05757102

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

Sponsor: GlaxoSmithKline

Columbia, MO · +27 more sites

RecruitingPhase 3NCT07361497

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

Sponsor: Bristol-Myers Squibb

Columbia, MO · +37 more sites

RecruitingPhase 3NCT07361510

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Sponsor: Bristol-Myers Squibb

Columbia, MO · +40 more sites

RecruitingPhase 3NCT07645248

A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

Sponsor: GlaxoSmithKline

Columbia, MO · +11 more sites

RecruitingPhase 3NCT06819891

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Columbia, MO · St Louis, MO · +59 more sites

RecruitingPhase 2NCT06548542

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

Sponsor: AbbVie

Columbia, MO · Liberty, MO · St Louis, MO · +61 more sites

RecruitingNot applicableNCT06545045

Cognitive Rehabilitation Following Breast Cancer Treatment

Sponsor: University of Missouri-Columbia

Columbia, MO

RecruitingPhase 3NCT04293562

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Sponsor: Children's Oncology Group

Columbia, MO · Kansas City, MO · St Louis, MO · +183 more sites

RecruitingPhase 3NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Sponsor: Ascletis Pharma (China) Co., Limited

Columbia, MO · St Louis, MO · +82 more sites

RecruitingPhase 3NCT06677060

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Sponsor: AstraZeneca

Columbia, MO · Kansas City, MO · +195 more sites

RecruitingPhase 3NCT06979453

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

Sponsor: Bristol-Myers Squibb

Columbia, MO · Lee's Summit, MO · +44 more sites

RecruitingPhase 3NCT05879926

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Sponsor: NRG Oncology

Ballwin, MO · Bolivar, MO · Branson, MO · +1223 more sites

RecruitingPhase 1 / Phase 2NCT04726241

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Sponsor: PedAL BCU, LLC

Columbia, MO · Kansas City, MO · St Louis, MO · +161 more sites

RecruitingPhase not listedNCT00271180

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Sponsor: Medtronic

Columbia, MO · Kansas City, MO · St Louis, MO · +110 more sites

RecruitingNot applicableNCT06335771

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

Sponsor: Bettina Mittendorfer

Columbia, MO

RecruitingPhase not listedNCT06571474

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Sponsor: Bettina Mittendorfer

Columbia, MO

RecruitingPhase 3NCT05812807

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Sponsor: Alliance for Clinical Trials in Oncology

Ballwin, MO · Cape Girardeau, MO · City of Saint Peters, MO · +825 more sites

RecruitingNot applicableNCT07231484

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

Sponsor: University of Missouri-Columbia

Columbia, MO

RecruitingEarly Phase 1NCT05219799

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Sponsor: University of Missouri-Columbia

Columbia, MO

RecruitingNot applicableNCT03887715

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Sponsor: LivaNova

Columbia, MO · O'Fallon, MO · St Louis, MO · +98 more sites

RecruitingPhase not listedNCT01790152

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

Sponsor: Children's Oncology Group

Columbia, MO · St Louis, MO · +67 more sites

RecruitingPhase not listedNCT06571500

Growth Hormone Resistance of Beta-cells in People With a Family History of Type 2 Diabetes

Sponsor: University of Missouri-Columbia

Columbia, MO

RecruitingPhase not listedNCT07083557

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Sponsor: Bettina Mittendorfer

Columbia, MO

RecruitingPhase not listedNCT02838836

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

Sponsor: University of Missouri-Columbia

Columbia, MO

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.