Clinical trials in Los Alamitos, CA

48 recruiting studies have a site in or near Los Alamitos, CA, California.

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Showing 40 of 48 studies

RecruitingPhase 3NCT05980949

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Anaheim, CA · Chino, CA · +145 more sites

RecruitingPhase 3NCT06819878

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Garden Grove, CA · Inglewood, CA · La Jolla, CA · +92 more sites

RecruitingPhase 3NCT06617325

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

Sponsor: UCB Biopharma SRL

Beverly Hills, CA · La Jolla, CA · +60 more sites

RecruitingPhase 2NCT07697456

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

Sponsor: AbbVie

Anaheim, CA · Coronado, CA · Lancaster, CA · +57 more sites

RecruitingPhase 1NCT06809400

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

Sponsor: Eli Lilly and Company

Los Alamitos, CA · +10 more sites

RecruitingPhase 3NCT07577843

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Chula Vista, CA · Los Alamitos, CA · +19 more sites

RecruitingPhase 3NCT06312176

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Sponsor: Merck Sharp & Dohme LLC

Fullerton, CA · La Jolla, CA · Los Alamitos, CA · +43 more sites

RecruitingPhase 3NCT07577856

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Chula Vista, CA · Los Alamitos, CA · +21 more sites

RecruitingPhase 3NCT07222566

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Sponsor: Pfizer

Anaheim, CA · Fountain Valley, CA · +223 more sites

RecruitingPhase 1NCT07787169

A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease

Sponsor: Eli Lilly and Company

Anaheim, CA · Irvine, CA · Los Alamitos, CA · +10 more sites

RecruitingPhase 3NCT06937086

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Sponsor: Eli Lilly and Company

Anaheim, CA · Beverly Hills, CA · Los Alamitos, CA · +34 more sites

RecruitingPhase 3NCT06937099

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Sponsor: Eli Lilly and Company

Anaheim, CA · Beverly Hills, CA · Los Alamitos, CA · +32 more sites

RecruitingPhase 3NCT06790693

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

Sponsor: Hoffmann-La Roche

Burbank, CA · Irvine, CA · La Jolla, CA · +59 more sites

RecruitingPhase 2NCT07432958

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

Sponsor: Appello Pharmaceuticals, Inc.

Carlsbad, CA · Los Alamitos, CA · Los Angeles, CA · +27 more sites

RecruitingPhase 3NCT06283966

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Sponsor: AstraZeneca

Apple Valley, CA · Canoga Park, CA · Castroville, CA · +232 more sites

RecruitingPhase 3NCT07361510

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Sponsor: Bristol-Myers Squibb

Beverly Hills, CA · Fountain Valley, CA · Los Alamitos, CA · +38 more sites

RecruitingPhase 3NCT07564414

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

Sponsor: Novo Nordisk A/S

Escondido, CA · La Mesa, CA · +96 more sites

RecruitingPhase 2NCT06540833

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

Sponsor: Intra-Cellular Therapies, Inc.

Anaheim, CA · Los Alamitos, CA · Newport Beach, CA · +25 more sites

RecruitingPhase 3NCT05646862

A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy

Sponsor: Hoffmann-La Roche

Greenbrae, CA · Los Alamitos, CA · Los Angeles, CA · +36 more sites

RecruitingPhase 3NCT06559306

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Colton, CA · Encino, CA · +81 more sites

RecruitingPhase 3NCT06742723

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Sponsor: AstraZeneca

Beverly Hills, CA · Canoga Park, CA · Concord, CA · +130 more sites

RecruitingPhase 3NCT07225946

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

Sponsor: Janssen Research & Development, LLC

Fountain Valley, CA · La Jolla, CA · Los Alamitos, CA · +56 more sites

RecruitingPhase 3NCT07499232

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Janssen Research & Development, LLC

Anaheim, CA · Lancaster, CA · Los Alamitos, CA · +36 more sites

RecruitingPhase 2 / Phase 3NCT07063745

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Sponsor: Bristol-Myers Squibb

Los Alamitos, CA · Los Angeles, CA · +41 more sites

RecruitingNot applicableNCT07214532

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Sponsor: Natera, Inc.

Greenbrae, CA · Loma Linda, CA · Los Alamitos, CA · +46 more sites

RecruitingPhase 1NCT07734493

A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia

Sponsor: Leal Therapeutics, Inc

Los Alamitos, CA · +9 more sites

RecruitingPhase 3NCT06492616

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Sponsor: Stemline Therapeutics, Inc.

Bakersfield, CA · Berkeley, CA · Beverly Hills, CA · +173 more sites

RecruitingPhase 2NCT07145918

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Sponsor: AbbVie

Glendale, CA · Los Alamitos, CA · +5 more sites

RecruitingPhase 2NCT07415954

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Sponsor: Novo Nordisk A/S

Lancaster, CA · Lomita, CA · Long Beach, CA · +20 more sites

RecruitingPhase 3NCT06252649

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Sponsor: Amgen

Fullerton, CA · Long Beach, CA · Los Alamitos, CA · +23 more sites

RecruitingPhase 1NCT07061288

A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

Sponsor: Bristol-Myers Squibb

Los Alamitos, CA · +7 more sites

RecruitingPhase 3NCT07797335

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

Sponsor: Novo Nordisk A/S

Lancaster, CA · Lincoln, CA · Lomita, CA · +106 more sites

RecruitingPhase 3NCT07662044

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus

Sponsor: AstraZeneca

Lomita, CA · Los Alamitos, CA · San Diego, CA · +24 more sites

RecruitingPhase 3NCT07567001

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Sponsor: Novo Nordisk A/S

Alhambra, CA · Beverly Hills, CA · +203 more sites

RecruitingPhase 4NCT07611214

PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

Sponsor: Aurinia Pharmaceuticals Inc.

La Mesa, CA · Los Alamitos, CA · +25 more sites

RecruitingPhase 2NCT06991114

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Sponsor: Artiva Biotherapeutics, Inc.

Chula Vista, CA · Covina, CA · Los Alamitos, CA · +28 more sites

RecruitingPhase not listedNCT06398626

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Sponsor: Pfizer

La Jolla, CA · Los Alamitos, CA · +25 more sites

RecruitingPhase 1NCT04389632

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Anaheim, CA · Fullerton, CA · +103 more sites

RecruitingPhase 2NCT07191483

A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

Sponsor: Kynexis B.V.

Cerritos, CA · Lemon Grove, CA · Los Alamitos, CA · +12 more sites

RecruitingPhase 1NCT06657768

A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

Sponsor: Eli Lilly and Company

Los Alamitos, CA · +10 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.