RecruitingNot applicableNCT07883720
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
Sponsor: Brigham and Women's Hospital
Boston, MA
Parkinson's Disease clinical trials in Boston, MA
33 recruiting parkinson's disease studies with a site in Boston, MA.
RecruitingPhase 3NCT06623422
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Sponsor: Merck Sharp & Dohme LLC
Boston, MA · +52 more sites
RecruitingPhase not listedNCT02071134
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
Sponsor: Boston Scientific Corporation
Boston, MA · +28 more sites
RecruitingPhase 3NCT06312176
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Sponsor: Merck Sharp & Dohme LLC
Boston, MA · +45 more sites
RecruitingPhase 3NCT06952504
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Sponsor: Merck Sharp & Dohme LLC
Boston, MA · +52 more sites
RecruitingPhase 3NCT06966700
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Sponsor: Merck Sharp & Dohme LLC
Boston, MA · +62 more sites
RecruitingPhase 3NCT06989112
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Sponsor: AstraZeneca
Boston, MA · Worcester, MA · +61 more sites
RecruitingPhase 2NCT06996652
An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)
Sponsor: Yale University
Boston, MA · +16 more sites
RecruitingPhase 3NCT07174310
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Sponsor: Hoffmann-La Roche
Boston, MA · +52 more sites
RecruitingPhase 2NCT07432958
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Sponsor: Appello Pharmaceuticals, Inc.
Boston, MA · +29 more sites
RecruitingPhase 2NCT06680830
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Sponsor: Neuron23 Inc.
Boston, MA · +44 more sites
RecruitingPhase 2 / Phase 3NCT06976268
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
Sponsor: Biohaven Therapeutics Ltd.
Boston, MA · Foxborough, MA · +22 more sites
RecruitingPhase not listedNCT07567794
GBPDC: Gut-Brain in PD Consortium Master Protocol
Sponsor: Duke University
Boston, MA · +6 more sites
RecruitingPhase 2NCT07005180
Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
Sponsor: Hillhurst Biopharmaceuticals, Inc.
Boston, MA · +7 more sites
RecruitingPhase 2NCT07002034
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Sponsor: Reunion Neuroscience Inc
Boston, MA · Worcester, MA · +30 more sites
RecruitingPhase not listedNCT04994015
Parkinson's Foundation PD GENEration Genetic Registry
Sponsor: Parkinson's Foundation
Boston, MA · +60 more sites
RecruitingPhase not listedNCT07330258
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
Sponsor: Bayer
Boston, MA · +26 more sites
RecruitingPhase 1 / Phase 2NCT04165070
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Sponsor: Merck Sharp & Dohme LLC
Boston, MA · +16 more sites
RecruitingPhase not listedNCT04165798
KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)
Sponsor: Merck Sharp & Dohme LLC
Boston, MA · +16 more sites
RecruitingNot applicableNCT07705373
A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease
Sponsor: Boston University Charles River Campus
Boston, MA · +2 more sites
RecruitingPhase 3NCT06944522
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
Sponsor: BlueRock Therapeutics
Boston, MA · +32 more sites
RecruitingPhase not listedNCT04477785
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
Sponsor: Michael J. Fox Foundation for Parkinson's Research
Boston, MA · +28 more sites
RecruitingPhase not listedNCT01799915
Natural History Study of Synucleinopathies
Sponsor: NYU Langone Health
Boston, MA · +4 more sites
RecruitingNot applicableNCT06425731
Dance and Energy Expenditure Among Adults With Parkinson's
Sponsor: Northeastern University
Boston, MA
RecruitingNot applicableNCT04286308
Cortical-Basal Ganglia Speech Networks
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingPhase 1NCT06687837
Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons
Sponsor: Jeffrey S. Schweitzer, MD, PhD
Boston, MA
RecruitingPhase not listedNCT04991831
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
Sponsor: InSightec
Boston, MA · +6 more sites
RecruitingNot applicableNCT07455760
Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients
Sponsor: Boston University Charles River Campus
Boston, MA
RecruitingPhase not listedNCT04071847
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Sponsor: Abbott Medical Devices
Boston, MA · +22 more sites
RecruitingNot applicableNCT05317390
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
Sponsor: Massachusetts Eye and Ear Infirmary
Boston, MA
RecruitingNot applicableNCT06602544
Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease
Sponsor: Harvard Medical School (HMS and HSDM)
Allston, MA · Boston, MA
Not yet recruitingPhase 4NCT07793461
Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics
Sponsor: Beth Israel Deaconess Medical Center
Boston, MA
Not yet recruitingPhase not listedNCT04753320
Remote Monitoring in Progressive Supranuclear Palsy (PSP)
Sponsor: Massachusetts General Hospital
Boston, MA · +1 more sites
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.