Phase 3 Obesity clinical trials

41 recruiting Phase 3 obesity studies in the US. What trial phases mean

Other phases

RecruitingPhase 3NCT07654374

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Birmingham, AL · Chandler, AZ · Phoenix, AZ · +71 more sites

RecruitingPhase 3NCT07845500

A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity

Sponsor: Pfizer

Birmingham, AL · Los Angeles, CA · Santa Ana, CA · +13 more sites

RecruitingPhase 3NCT07351045

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

Sponsor: Hoffmann-La Roche

Anniston, AL · Birmingham, AL · +41 more sites

RecruitingPhase 3NCT07595549

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

Sponsor: Pfizer

Canoga Park, CA · Escondido, CA · Modesto, CA · +32 more sites

RecruitingPhase 3NCT07667803

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

Sponsor: AstraZeneca

Birmingham, AL · Dothan, AL · Chandler, AZ · +53 more sites

RecruitingPhase 3NCT07823608

A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)

Sponsor: Pfizer

Cullman, AL · Riverside, CA · Bradenton, FL · +3 more sites

RecruitingPhase 3NCT07037433

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Sponsor: Amgen

Daphne, AL · Fairhope, AL · Huntsville, AL · +137 more sites

RecruitingPhase 3NCT07794579

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

Sponsor: Eli Lilly and Company

Anniston, AL · Birmingham, AL · Pelham, AL · +77 more sites

RecruitingPhase 3NCT06672549

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Sponsor: Eli Lilly and Company

Tucson, AZ · Loma Linda, CA · Los Angeles, CA · +47 more sites

RecruitingPhase 3NCT06937086

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Sponsor: Eli Lilly and Company

Dothan, AL · Anaheim, CA · Beverly Hills, CA · +34 more sites

RecruitingPhase 3NCT06937099

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Sponsor: Eli Lilly and Company

Dothan, AL · Anaheim, CA · Beverly Hills, CA · +32 more sites

RecruitingPhase 3NCT07843472

A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Established Cardiovascular Disease

Sponsor: Hoffmann-La Roche

Anniston, AL · Los Angeles, CA · Port Orange, FL

RecruitingPhase 3NCT07843498

A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity

Sponsor: Hoffmann-La Roche

Anniston, AL · Port Orange, FL · Nashville, TN

RecruitingPhase 3NCT07684235

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

Sponsor: Amgen

Anniston, AL · Daphne, AL · Mobile, AL · +68 more sites

RecruitingPhase 3NCT07253285

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

Sponsor: Novo Nordisk A/S

Escondido, CA · Hollywood, FL · Jacksonville, FL · +31 more sites

RecruitingPhase 3NCT07533175

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Sponsor: Novo Nordisk A/S

Birmingham, AL · Escondido, CA · Lomita, CA · +12 more sites

RecruitingPhase 3NCT07564414

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

Sponsor: Novo Nordisk A/S

Birmingham, AL · Pelham, AL · Gilbert, AZ · +96 more sites

RecruitingPhase 3NCT07668414

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

Sponsor: Novo Nordisk A/S

Lancaster, CA · Palm Springs, CA · Pomona, CA · +42 more sites

RecruitingPhase 3NCT07776509

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

Sponsor: AstraZeneca

Escondido, CA · Lincoln, CA · Walnut Creek, CA · +20 more sites

RecruitingPhase 3NCT06439277

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Sponsor: Eli Lilly and Company

Los Angeles, CA · Sacramento, CA · Wilmington, DE · +11 more sites

RecruitingPhase 3NCT07339423

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

Sponsor: Novo Nordisk A/S

Miramar, FL · Orlando, FL · Conyers, GA · +19 more sites

RecruitingPhase 3NCT07321886

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

Sponsor: Eli Lilly and Company

Tuscaloosa, AL · Scottsdale, AZ · Escondido, CA · +38 more sites

RecruitingPhase 3NCT07784270

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

Sponsor: AstraZeneca

Fairhope, AL · Huntsville, AL · Mobile, AL · +51 more sites

RecruitingPhase 3NCT07037459

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Sponsor: Amgen

Birmingham, AL · Dothan, AL · Fairhope, AL · +118 more sites

RecruitingPhase 3NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Sponsor: Ascletis Pharma (China) Co., Limited

Birmingham, AL · Huntsville, AL · Peoria, AZ · +81 more sites

RecruitingPhase 3NCT07745504

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

Sponsor: Novo Nordisk A/S

Conyers, GA · Honolulu, HI · Oak Park, IL · +8 more sites

RecruitingPhase 3NCT05819853

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

Sponsor: University of Colorado, Denver

Aurora, CO

RecruitingPhase 3NCT06366464

A Study of Pitolisant in Patients With Prader-Willi Syndrome

Sponsor: Harmony Biosciences Management, Inc.

Los Angeles, CA · Sacramento, CA · San Diego, CA · +20 more sites

RecruitingPhase 3NCT07654361

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Birmingham, AL · Phoenix, AZ · +68 more sites

RecruitingPhase 3NCT07481630

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Sponsor: Novo Nordisk A/S

Phoenix, AZ · Walnut Creek, CA · Hamden, CT · +16 more sites

RecruitingPhase 3NCT07446439

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

Sponsor: Vanda Pharmaceuticals

Los Angeles, CA · San Diego, CA · San Jose, CA · +7 more sites

RecruitingPhase 3NCT06760546

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Sponsor: Rhythm Pharmaceuticals, Inc.

Birmingham, AL · Aurora, CO · Chicago, IL · +5 more sites

Not yet recruitingPhase 3NCT07881432

A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes

Sponsor: Eli Lilly and Company

Mesa, AZ · Scottsdale, AZ · Tucson, AZ · +52 more sites

Not yet recruitingPhase 3NCT07881458

A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes

Sponsor: Eli Lilly and Company

Tucson, AZ · Los Alamitos, CA · Los Angeles, CA · +22 more sites

Not yet recruitingPhase 3NCT07881757

A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)

Sponsor: Pfizer

Bradenton, FL · Tomball, TX

Not yet recruitingPhase 3NCT07850050

SYNCHRONIZE®-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight

Sponsor: Boehringer Ingelheim

Birmingham, AL · Northridge, CA · Walnut Creek, CA · +10 more sites

Not yet recruitingPhase 3NCT07871409

Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight

Sponsor: Amgen

The Villages, FL

Not yet recruitingPhase 3NCT07855900

SYNCHRONIZE®-START- A Study to Test Whether Survodutide Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight

Sponsor: Boehringer Ingelheim

Riverview, FL

Not yet recruitingPhase 3NCT07021937

Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity

Sponsor: University of Colorado, Denver

Aurora, CO

Not yet recruitingPhase 3NCT07298915

The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED)

Sponsor: University of Virginia

Charlottesville, VA

Not yet recruitingPhase 3NCT07400107

AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Sponsor: Novo Nordisk A/S

Hollywood, FL · Orange City, FL · Weston, FL · +7 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.