RecruitingPhase 2NCT07752979
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
Sponsor: AbbVie
Pelham, AL · Scottsdale, AZ · Tucson, AZ · +56 more sites
Phase 2 Obesity clinical trials
44 recruiting Phase 2 obesity studies in the US. What trial phases mean
Other phases
RecruitingPhase 2NCT06273072
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
Sponsor: Johns Hopkins University
Baltimore, MD · Houston, TX
RecruitingPhase 2NCT07837973
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss
Sponsor: Alveus Therapeutics, Inc.
Birmingham, AL · Sun City, AZ · Tempe, AZ · +17 more sites
RecruitingPhase 2NCT07685808
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
Sponsor: Regeneron Pharmaceuticals
Mobile, AL · Walnut Creek, CA · Waterbury, CT · +18 more sites
RecruitingPhase 2NCT06897475
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Sponsor: Eli Lilly and Company
Phoenix, AZ · Santa Ana, CA · Ocala, FL · +22 more sites
RecruitingPhase 2NCT07589608
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Sponsor: Eli Lilly and Company
Chandler, AZ · Scottsdale, AZ · Tucson, AZ · +37 more sites
RecruitingPhase 2NCT07783802
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Sponsor: Eli Lilly and Company
Huntsville, AL · Tucson, AZ · +27 more sites
RecruitingPhase 2NCT06143956
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Sponsor: Eli Lilly and Company
Chandler, AZ · Phoenix, AZ · Scottsdale, AZ · +47 more sites
RecruitingPhase 2NCT07282340
Phentermine's Impact on Treatment in Teens
Sponsor: Russell McCulloh, MD
Wilmington, DE · Louisville, KY · Baton Rouge, LA · +5 more sites
RecruitingPhase 2NCT06173778
Semaglutide for Post-Smoking Cessation Weight Management
Sponsor: The University of Texas Health Science Center, Houston
Austin, TX · Houston, TX
RecruitingPhase 2NCT06847399
Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder
Sponsor: Johns Hopkins University
Baltimore, MD
RecruitingPhase 2NCT05770570
Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
Sponsor: Memorial Sloan Kettering Cancer Center
New York, NY
RecruitingPhase 2NCT06137365
Cannabis for Obesity Trial
Sponsor: Joshua A. Lile, Ph.D.
Lexington, KY
RecruitingPhase 2NCT06899178
Atomoxetine in Melanocortin Obesity Syndrome
Sponsor: Icahn School of Medicine at Mount Sinai
New York, NY · Columbus, OH · Nashville, TN
RecruitingPhase 2NCT06411210
Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment
Sponsor: Yale University
New Haven, CT
RecruitingPhase 2NCT05173714
Sit Less, Interact and Move More (SLIMM) 2 Study
Sponsor: Srinvasan Beddhu
Stanford, CA · Salt Lake City, UT
RecruitingPhase 2NCT07332741
FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
Sponsor: University of Illinois at Chicago
Chicago, IL · +1 more sites
RecruitingPhase 2NCT04551482
Oxytocin for Weight Loss in Adolescents
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingPhase 2NCT07570758
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
Sponsor: ERX Pharmaceuticals
Louisville, KY · Monroe, NC · North Charleston, SC
RecruitingPhase 2NCT07228741
Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity
Sponsor: St. Jude Children's Research Hospital
Memphis, TN
RecruitingPhase 2NCT06554717
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
Sponsor: Massachusetts General Hospital
Aurora, CO · Boston, MA
RecruitingPhase 2NCT06903923
Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy
Sponsor: University of Virginia
Charlottesville, VA
RecruitingPhase 2NCT06811324
Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults
Sponsor: The University of Texas Health Science Center at San Antonio
San Antonio, TX
RecruitingPhase 2NCT05933499
Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingPhase 2NCT07487090
Fasted vs. Fed State Exercise
Sponsor: Arkansas Colleges of Health Education
Fort Smith, AR
RecruitingPhase 2NCT06717698
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
Sponsor: Novo Nordisk A/S
San Dimas, CA · San Ramon, CA · Aurora, CO · +15 more sites
RecruitingPhase 2NCT06623669
A Mobile Intervention to Reduce Pain and Improve Health-III
Sponsor: Wake Forest University
Winston-Salem, NC
RecruitingPhase 2NCT06517212
Tirzepatide Weight Loss for MRD+ Early Breast Cancer
Sponsor: Baylor Research Institute
Dallas, TX
RecruitingPhase 2NCT05903131
Uterine Preservation Via Lifestyle Transformation
Sponsor: Washington University School of Medicine
St Louis, MO · Albuquerque, NM · Oklahoma City, OK
RecruitingPhase 2NCT06802081
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
Sponsor: The Cleveland Clinic
Cleveland, OH
RecruitingPhase 2NCT06745063
Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity
Sponsor: VA Office of Research and Development
Columbia, MO
RecruitingPhase 2NCT06994338
Tirzepatide for Alcohol Use Disorder
Sponsor: University of Southern California
Los Angeles, CA
RecruitingPhase 2NCT03762395
Anti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma
Sponsor: University of Colorado, Denver
Aurora, CO
RecruitingPhase 2NCT05301413
Social Determinants and a Diabetes Prevention Program Tailored for African Americans
Sponsor: University of Missouri, Kansas City
Kansas City, MO
RecruitingPhase 2NCT06028113
A Novel Obesity Prevention Program for High-Risk Infants in Primary Care
Sponsor: Children's Hospital Medical Center, Cincinnati
Cincinnati, OH
RecruitingPhase 2NCT05912621
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
Sponsor: Stanford University
Palo Alto, CA
RecruitingPhase 2NCT04721873
Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
Sponsor: University of California, San Diego
La Jolla, CA
Not yet recruitingPhase 2NCT07874828
PROACT AYA: Preventing Overweight/Obesity-Associated Cardiotoxicity With Tirzepatide In Adolescent And Young Adult Cancer Survivors - A Phase 2 Single-Arm, Single-Center Feasibility Study
Sponsor: M.D. Anderson Cancer Center
Houston, TX
Not yet recruitingPhase 2NCT07820358
Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical Hyperplasia and Grade 1 Endometrial Cancer
Sponsor: The Methodist Hospital Research Institute
Houston, TX · +1 more sites
Not yet recruitingPhase 2NCT07760948
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide
Sponsor: Vanderbilt University Medical Center
Nashville, TN
Not yet recruitingPhase 2NCT07349641
A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer
Sponsor: National Cancer Institute (NCI)
Chicago, IL · Houston, TX
Not yet recruitingPhase 2NCT07747805
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
Sponsor: The Cleveland Clinic
Cleveland, OH
Not yet recruitingPhase 2NCT07534332
Disulfiram in Rheumatoid Arthritis
Sponsor: University of Oklahoma
Oklahoma City, OK
Not yet recruitingPhase 2NCT06320951
VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway
Sponsor: University of Alabama at Birmingham
Birmingham, AL
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.